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Recombinant TRIM29 抗体 (AA 1-200)

This 兔 单克隆 antibody specifically detects TRIM29 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7868783
发货至: 中国
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Quick Overview for Recombinant TRIM29 抗体 (AA 1-200) (ABIN7868783)

抗原

See all TRIM29 抗体
TRIM29 (Tripartite Motif Containing 29 (TRIM29))

抗体类型

Recombinant Antibody

适用

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宿主

  • 46
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克隆类型

  • 42
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单克隆

标记

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This TRIM29 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

TRIM29-9256R
  • 抗原表位

    • 33
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    AA 1-200

    原理

    Recombinant TRIM29 Antibody / Tripartite motif-containing protein 29

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant fragment (within amino acids 1-200) of human TRIM29 protein was used as the immunogen for the recombinant TRIM29 antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the recombinant TRIM29 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant TRIM29 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    TRIM29 (Tripartite Motif Containing 29 (TRIM29))

    别名

    TRIM29

    背景

    Tripartite motif-containing protein 29 (TRIM29) interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90 % positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.

    UniProt

    Q14134

    途径

    p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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