Recombinant TRIM29 抗体 (AA 1-200)
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北京 101111
Quick Overview for Recombinant TRIM29 抗体 (AA 1-200) (ABIN7868783)
抗原
See all TRIM29 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-200
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原理
- Recombinant TRIM29 Antibody / Tripartite motif-containing protein 29
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant fragment (within amino acids 1-200) of human TRIM29 protein was used as the immunogen for the recombinant TRIM29 antibody.
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亚型
- IgG, kappa
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应用备注
- Optimal dilution of the recombinant TRIM29 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant TRIM29 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- TRIM29 (Tripartite Motif Containing 29 (TRIM29))
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别名
- TRIM29
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背景
- Tripartite motif-containing protein 29 (TRIM29) interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90 % positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.
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UniProt
- Q14134
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途径
- p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
抗原
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