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Recombinant MCM2 抗体 (AA 1-200)

The 兔 单克隆 anti-MCM2 antibody (Clone MCM2-8006R) (ABIN7868650) specifically detects MCM2 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7868650
发货至: 中国
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Quick Overview for Recombinant MCM2 抗体 (AA 1-200) (ABIN7868650)

抗原

See all MCM2 抗体
MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This MCM2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

MCM2-8006R
  • 抗原表位

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    AA 1-200

    原理

    MCM2 Antibody (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the MCM2 antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the MCM2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the MCM2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

    别名

    MCM2

    背景

    The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.

    UniProt

    P49736

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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