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Kallikrein 4 抗体 (AA 1-200)

The 小鼠 单克隆 anti-Kallikrein 4 antibody (Clone KLK4-8941) (ABIN7868620) specifically detects Kallikrein 4 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7868620
发货至: 中国
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Quick Overview for Kallikrein 4 抗体 (AA 1-200) (ABIN7868620)

抗原

See all Kallikrein 4 (KLK4) 抗体
Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))

适用

  • 35
  • 9
  • 4

宿主

  • 28
  • 15
小鼠

克隆类型

  • 28
  • 15
单克隆

标记

  • 31
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Kallikrein 4 antibody is un-conjugated

应用范围

  • 23
  • 19
  • 7
  • 6
  • 6
  • 6
  • 3
  • 2
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

KLK4-8941
  • 抗原表位

    • 11
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-200

    原理

    KLK4 Antibody / Kallikrein 4 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant fragment of human KLK4 protein (within amino acids 1-200) was used as the immunogen for the KLK4 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the KLK4 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Aliquot the KLK4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))

    别名

    KLK4

    背景

    Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes. Human pancreatic/renal KLK encodes for the KLK1 enzyme, which is involved in post-translational processing of polypeptide precursors. The function of the other members of KLK gene family is still currently unknown, but evidence suggests that many KLKs are implicated in carcinogenesis. The human KLK gene family consists of 15 serine proteases. The human KLK genes are clustered on chromosome 19q13. Unlike other kalllikreins, the KLK4-15 encoded proteases are less related and do not contain a conventional KLK loop. Clusters of genes exhibit high prostatic (KLK2-4, KLK15) or pancreatic (KLK6-13) expression. KLK2 is also known as glandular kallikrein 2, tissue kallikrein, or HGK-1 and KLK3 is known as prostate-specific antigen (PSA). Both KLK2 and KLK3 have important applications in prostate cancer and breast cancer diagnostics. Many of the KLKs are regulated by steroid hormones and a few of them, specifically KLK3, KLK6 and KLK10, are known to be downregulated in breast and other cancers. KLK4 expression is abundant in skin, mammary gland and testis.

    UniProt

    Q9Y5K2

    途径

    Complement System
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