Kallikrein 4 抗体 (AA 1-200)
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Quick Overview for Kallikrein 4 抗体 (AA 1-200) (ABIN7868619)
抗原
See all Kallikrein 4 (KLK4) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-200
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原理
- Kallikrein 4 Antibody / KLK4
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant fragment of human Kallikrein 4 protein (within amino acids 1-200) was used as the immunogen for the Kallikrein 4 antibody.
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亚型
- IgG2b, kappa
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anti-Kallikrein-Related Peptidase 4 (KLK4) (AA 32-256) antibody
KLK4 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein-Related Peptidase 4 (KLK4) (AA 32-255) antibodyKLK4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein-Related Peptidase 4 (KLK4) (AA 159-254) antibodyKLK4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A4 unconjugated
anti-Kallikrein-Related Peptidase 4 (KLK4) (AA 30-254) antibodyKLK4 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein-Related Peptidase 4 (KLK4) (AA 31-254) antibodyKLK4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein-Related Peptidase 4 (KLK4) (AA 27-254) antibodyKLK4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein-Related Peptidase 4 (KLK4) (AA 85-115) antibodyKLK4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB6105 unconjugated
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应用备注
- Optimal dilution of the Kallikrein 4 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot the Kallikrein 4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))
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别名
- Kallikrein 4
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背景
- Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes. Human pancreatic/renal KLK encodes for the KLK1 enzyme, which is involved in post-translational processing of polypeptide precursors. The function of the other members of KLK gene family is still currently unknown, but evidence suggests that many KLKs are implicated in carcinogenesis. The human KLK gene family consists of 15 serine proteases. The human KLK genes are clustered on chromosome 19q13. Unlike other kalllikreins, the KLK4-15 encoded proteases are less related and do not contain a conventional KLK loop. Clusters of genes exhibit high prostatic (KLK2-4, KLK15) or pancreatic (KLK6-13) expression. KLK2 is also known as glandular kallikrein 2, tissue kallikrein, or HGK-1 and KLK3 is known as prostate-specific antigen (PSA). Both KLK2 and KLK3 have important applications in prostate cancer and breast cancer diagnostics. Many of the KLKs are regulated by steroid hormones and a few of them, specifically KLK3, KLK6 and KLK10, are known to be downregulated in breast and other cancers. KLK4 expression is abundant in skin, mammary gland and testis.
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UniProt
- Q9Y5K2
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途径
- Complement System
抗原
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