SIGMAR1 抗体 (AA 1-154)
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Quick Overview for SIGMAR1 抗体 (AA 1-154) (ABIN7868213)
抗原
See all SIGMAR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-154
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原理
- Sigma1-receptor Antibody / SIGMAR1
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids G1-H154) was used as the immunogen for the Sigma1-receptor antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Sigma1-receptor antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Sigma1-receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
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别名
- Sigma1-receptor
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背景
- The sigma-1 receptor, one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor. In humans, the sigma-1 receptor is encoded by the SIGMAR1 gene. This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor, it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
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UniProt
- Q99720
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途径
- SARS-CoV-2 Protein Interactome
抗原
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