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HDAC7 抗体 (pSer358) (Cy5.5)

HDAC7 适用: 小鼠, 大鼠 IF (cc), IF (p) 宿主: 兔 Polyclonal Cy5.5
产品编号 ABIN743008
发货至: 中国
  • 抗原 See all HDAC7 抗体
    HDAC7 (Histone Deacetylase 7 (HDAC7))
    抗原表位
    • 18
    • 14
    • 12
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer358
    适用
    • 110
    • 73
    • 53
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 118
    • 6
    克隆类型
    • 112
    • 12
    多克隆
    标记
    • 52
    • 10
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    This HDAC7 antibody is conjugated to Cy5.5
    应用范围
    • 78
    • 49
    • 25
    • 14
    • 13
    • 13
    • 10
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human HDAC7 around the phosphorylation site of Ser358
    亚型
    IgG
    Top Product
    Discover our top product HDAC7 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    HDAC7 (Histone Deacetylase 7 (HDAC7))
    别名
    HDAC7 (HDAC7 产品)
    别名
    HD7A antibody, HDAC7A antibody, 5830434K02Rik antibody, HD7 antibody, HD7a antibody, Hdac7a antibody, mFLJ00062 antibody, hdac7a antibody, K2K18.5 antibody, K2K18_5 antibody, histone deacetylase7 antibody, histone deacetylase 7 antibody, histone deacetylase7 antibody, HDAC7 antibody, Hdac7 antibody, hdac7 antibody, HDA7 antibody
    背景

    Synonyms: HDAC7 phospho S358, HDAC7 phospho Ser358, p-HDAC7 Ser358, HD 7a, HD7a, HDAC 7, HDAC 7A, HDAC7, HDAC7A, Histone deacetylase 7, Histone deacetylase 7A, DKFZP586J0917, OTTHUMP00000202813, OTTHUMP00000202814, FLJ99588, HDAC7_HUMAN.

    Background: HDAC7 is a member of the class II mammalian histone deacetylases, which plays an important role in modulating the eukaryotic chromatin structure. Human HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. It is an active component of different transcriptional corepressor complexes that can be recruited to specific promoter regions via interactions with a growing number of sequence specific transcriptional factors. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription.

    途径
    Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development
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