IL1A 抗体 (AA 113-271)
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北京 101111
Quick Overview for IL1A 抗体 (AA 113-271) (ABIN7862993)
抗原
See all IL1A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 113-271
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原理
- Interleukin-1 alpha (IL-1 alpha) Antibody
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特异性
- Two forms of interleukin-1, designated IL-1°™and IL-1 æ, have been described. Although encoded by distinct genes and exhibiting roughly only 25 % sequence identity, IL-1°™ and IL-1 æ bind to the same receptor and seem to elicit similar biological responses. IL-1 production is generally thought to be associated with inflammation, but it has also been shown to be expressed during kidney development, thymocyte differentiation and cartilage degradation. IL-1 plays a critical role in the regulation of immune response and inflammation, acting as an activator of T and B lymphocytes and natural killer (NK) cells. In T cells, IL-1 stimulates the production of IL-2 and selectively inhibits IL-4 expression. IL-1 induces B cell proliferation and maturation, and immunoglobulin synthesis. NK cells require IL-1 æ for production of the anti-pathogen IFN-Á. IL-1 has also been implicated in several pathological conditions including rheumatoid arthritis, inflammatory bowel disease and atherosclerosis.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa 113-271) of human IL1A protein
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亚型
- IgG2b, kappa
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anti-Interleukin 1 alpha (IL1A) (AA 177-206) antibody
IL1A 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21521 unconjugated
anti-Interleukin 1 alpha (IL1A) (AA 172-271) antibodyIL1A 适用: 人 WB, IP, ELISA, IF 宿主: 小鼠 Monoclonal 4F9 unconjugated
anti-Interleukin 1 alpha (IL1A) antibodyIL1A 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6G4A5 unconjugated
anti-Interleukin 1 alpha (IL1A) (AA 113-271) antibodyIL1A 适用: 人 WB 宿主: 小鼠 Monoclonal 3# unconjugated
anti-Interleukin 1 alpha (IL1A) (AA 90-268) antibodyIL1A 适用: 山羊 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C12 unconjugated
anti-Interleukin 1 alpha (IL1A) (AA 112-271) antibodyIL1A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 alpha (IL1A) (AA 177-206) antibodyIL1A 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 alpha (IL1A) (AA 115-270) antibodyIL1A 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C12 unconjugated
anti-Interleukin 1 alpha (IL1A) (N-Term) antibodyIL1A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 alpha (IL1A) (AA 113-271) antibodyIL1A 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- IL1A (Interleukin 1 alpha (IL1A))
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别名
- Interleukin-1 alpha
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背景
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BAF, FAF, Hematopoietin 1, IL 1 alpha, IL1F1, Interleukin 1 alpha, LAF, LEM, Preinterleukin 1 alpha, Pro interleukin 1 alpha
HeLa cells. Human colon carcinoma tissue.
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分子量
- 33kDa (proprotein), 17kDa (mature)
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基因ID
- 3552, 1722
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UniProt
- P01583
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途径
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
抗原
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