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Recombinant HLA-ABC 抗体 (AA 100-300)

This 兔 单克隆 antibody specifically detects HLA-ABC in WB 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN7859018
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant HLA-ABC 抗体 (AA 100-300) (ABIN7859018)

抗原

See all HLA-ABC 抗体
HLA-ABC

抗体类型

Recombinant Antibody

适用

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宿主

  • 68
  • 17
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克隆类型

  • 80
  • 9
单克隆

标记

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This HLA-ABC antibody is un-conjugated

应用范围

  • 65
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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

MHC-I-8147R
  • 抗原表位

    • 7
    • 1
    • 1
    AA 100-300

    原理

    Recombinant HLA Class 1 ABC (MHC I) Antibody

    特异性

    Major Histocompatibility Complex (MHC) is a genetic region on chromosomes composed of tightly linked highly polymorphic gene loci that encode cell surface specific proteins, depending on the structure and function of genes and coding products. We divide MHC into class 79oΩ 79oΩ, class 79oΩ 79oΩ and class 79oΩ 79oΩ gene regions. Endogenous antigen presentation is presented by the major histocompatibility complex 79oΩ 79oΩ (MHC 79oΩ 79oΩ) pathway. Intracytoplasmic proteins are decomposed into peptides during protease degradation, which in turn are delivered by HSP41 and HSP90 proteins to TAP on the membrane. MHC 79oΩ 79oΩ is widely distributed on the surface of almost all nucleated cells, including spleen, lymph nodes and thymus lymphocytes in normal tissues. It is also expressed in skin, lung, kidney, liver and heart tissues. It is also widely expressed in tumor tissues. MHC 79oΩ 79oΩmolecular typing is related to the matching of organ transplantation and bone marrow transplantation, as well as a variety of autoimmune diseases.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa100-300) of human HLA-I protein (exact sequence is proprietary)

    亚型

    IgG, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    HLA-ABC

    别名

    HLA Class 1 ABC

    背景

    Antigen Presenting Molecule, Cw*1701, D6S204, FLJ27082, HLA A, HLA B, HLA C, HLA class 1 A, HLA class 1 B, HLA class 1 C, HLA JY3, HLAA, HLAB, HLAC, HLC C, Human Leucocyte Antigen C, Major Histocompatibility Complex Class I A, Major Histocompatibility Complex Class I B, Major Histocompatibility Complex Class I C, Major histocompatibility complex, class I, A + B + C, MHC class I antigen A*1, MHC Class I Antigen, MHC class I antigen B*7, MHC class I antigen Cw*1, MHC class I HLA A, MHC class I HLA B, MHC class I HLA C, MHC HLA ABC,

    HOP-92, Lung, Hep G2, Human tonsil or lymph node. Human Spleen, Guinea pig Spleen, Human Lung or Guinea pig Lung

    分子量

    40/41kDa

    基因ID

    3105, 3106, 3107

    UniProt

    P01889, P30443, P30499

    途径

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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