Recombinant HLA-ABC 抗体 (AA 100-300)
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Quick Overview for Recombinant HLA-ABC 抗体 (AA 100-300) (ABIN7863894)
抗原
See all HLA-ABC 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 100-300
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原理
- Recombinant HLA Class 1 ABC (MHC I) Antibody
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特异性
- Major Histocompatibility Complex (MHC) is a genetic region on chromosomes composed of tightly linked highly polymorphic gene loci that encode cell surface specific proteins, depending on the structure and function of genes and coding products. We divide MHC into class 79oΩ 79oΩ, class 79oΩ 79oΩ and class 79oΩ 79oΩ gene regions. Endogenous antigen presentation is presented by the major histocompatibility complex 79oΩ 79oΩ (MHC 79oΩ 79oΩ) pathway. Intracytoplasmic proteins are decomposed into peptides during protease degradation, which in turn are delivered by HSP41 and HSP90 proteins to TAP on the membrane. MHC 79oΩ 79oΩ is widely distributed on the surface of almost all nucleated cells, including spleen, lymph nodes and thymus lymphocytes in normal tissues. It is also expressed in skin, lung, kidney, liver and heart tissues. It is also widely expressed in tumor tissues. MHC 79oΩ 79oΩmolecular typing is related to the matching of organ transplantation and bone marrow transplantation, as well as a variety of autoimmune diseases.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa100-300) of human HLA-I protein (exact sequence is proprietary)
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亚型
- IgG, kappa
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anti-HLA-ABC (HLA-ABC) antibody
HLA-ABC 适用: 人, Cow, Baboon, Cat, 猴 FACS, WB, IHC, IHC (fro), IP 宿主: 小鼠 Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibody (PE)HLA-ABC 适用: 人, Cow, Baboon, Cynomolgus, 猕猴, Macaque, Shrew, Chimpanzee, Gorilla FACS 宿主: 小鼠 Monoclonal W6-32 PE
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC 适用: 人, Cow, Baboon, Macaque, Cat, 猴, 灵长类, Chimpanzee FACS, IHC (fro), IF, IP, Func, EIA, DNA Mic 宿主: 小鼠 Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC 适用: 人, Cow, Cat, 猴, 灵长类 FACS, IHC (fro), IF, IP, EIA 宿主: 小鼠 Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibody (Biotin)HLA-ABC 适用: 人, Cow, Baboon, Cynomolgus, 猕猴, Macaque, Shrew FACS 宿主: 小鼠 Monoclonal W6-32 Biotin
anti-HLA-ABC (HLA-ABC) antibody (FITC)HLA-ABC 适用: 人, Cow, Baboon, Cynomolgus, 猕猴, Macaque, Shrew FACS 宿主: 小鼠 Monoclonal W6-32 FITC
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC 适用: 人 FACS, IHC, IHC (fro), IP 宿主: 大鼠 Monoclonal YTH862-2 unconjugated
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC 适用: 人, 小鼠, Non-Human Primate FACS, IF 宿主: 小鼠 Monoclonal 246-B8-E7 unconjugated
anti-HLA-ABC (HLA-ABC) antibody (PE)GMP Grade HLA-ABC 适用: 人, Baboon, Cynomolgus, 猕猴 FACS 宿主: 小鼠 Monoclonal W6-32 PE
anti-HLA-ABC (HLA-ABC) antibody (FITC)GMP Grade HLA-ABC 适用: 人, Baboon, Cynomolgus, 猕猴 FACS 宿主: 小鼠 Monoclonal W6-32 FITC
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- HLA-ABC
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别名
- HLA Class 1 ABC
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背景
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Antigen Presenting Molecule, Cw*1701, D6S204, FLJ27082, HLA A, HLA B, HLA C, HLA class 1 A, HLA class 1 B, HLA class 1 C, HLA JY3, HLAA, HLAB, HLAC, HLC C, Human Leucocyte Antigen C, Major Histocompatibility Complex Class I A, Major Histocompatibility Complex Class I B, Major Histocompatibility Complex Class I C, Major histocompatibility complex, class I, A + B + C, MHC class I antigen A*1, MHC Class I Antigen, MHC class I antigen B*7, MHC class I antigen Cw*1, MHC class I HLA A, MHC class I HLA B, MHC class I HLA C, MHC HLA ABC,
HOP-92, Lung, Hep G2, Human tonsil or lymph node. Human Spleen, Guinea pig Spleen, Human Lung or Guinea pig Lung
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分子量
- 40/41kDa
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基因ID
- 3105, 3106, 3107
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UniProt
- P01889, P30443, P30499
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途径
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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