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Recombinant LEF1 抗体 (AA 100-200)

The 兔 单克隆 anti-LEF1 antibody (Clone LEF1-422R) (ABIN7863218) specifically detects LEF1 in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7863218
发货至: 中国
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Quick Overview for Recombinant LEF1 抗体 (AA 100-200) (ABIN7863218)

抗原

See all LEF1 抗体
LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This LEF1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

LEF1-422R
  • 抗原表位

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    AA 100-200

    原理

    Recombinant LEF1 / TCF1 alpha (Transcription Factor) Antibody

    特异性

    Lymphoid Enhancing Factor 1 (LEF1) is a transcription factor that belongs to the TCF/LEF family. LEF1 participates as a regulator in Wnt signaling pathways. LEF1 is an important factor in lymphopoiesis and is expressed normally in T and pro-B cells but not expressed in mature B cells. Anti-LEF1 may be used as an aid for differentiation of chronic lymphocytic leukemia/small lymphocytic lymphoma from other small B cell lymphomas.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa100-200) of human LEF1 protein (exact sequence is proprietary)

    亚型

    IgG, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide store at 2 to 8 °C. Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

    别名

    LEF1

    背景

    Lymphoid enhancer-binding factor 1 (LEF1), T cell specific transcription factor 1 alpha (TCF1a), TCF1 alpha, TCF10, TCF7L3, Transcription factor T cell specific 1 alpha

    Human tonsil and thymus.

    分子量

    44kDa

    基因ID

    51176, 726506

    UniProt

    Q9UJU2

    途径

    WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding
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