RPA1 抗体
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北京 101111
Quick Overview for RPA1 抗体 (ABIN7833814)
抗原
See all RPA1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-RFa1/Rpa1 | Replication factor protein 1 (Saccharomyces cerevisiae)
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交叉反应 (详细)
- Saccharomyces cerevisiae
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免疫原
- Purified
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应用备注
- 1: 200 (IP), 1 : 2000 (WB)
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Serum. Contains 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube
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储存条件
- -20 °C
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储存方法
- Store at -20°C, make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
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- RPA1 (Replication Protein A1, 70kDa (RPA1))
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别名
- RFa1/Rpa1
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背景
- Rfa1 (Replication Factor A protein 1) as part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. Binds to single-stranded sequences participating in DNA replication in addition to those mediating transcriptional repression (URS1) and activation (CAR1). Stimulates the activity of a cognate strand exchange protein (SEP1). It cooperates with T-AG and DNA topoisomerase I to unwind template DNA containing the simian virus 40 origin of DNA replication.
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分子量
- 70.3 kDa
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基因ID
- 851266
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UniProt
- P22336
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途径
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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