PSME4 抗体 (AA 840-1140)
Our Local Distributor
北京 101111
Quick Overview for PSME4 抗体 (AA 840-1140) (ABIN7833480)
抗原
See all PSME4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 840-1140
-
原理
- Anti-PA200 | Proteasome activator PA200
-
交叉反应 （详细）
-
Arabidopsis thaliana
Not reactive in: No confirmed exceptions from predicted reactivity are currently known -
纯化方法
- Serum
-
免疫原
- PA200 antibodies were generated against a partial fragment encompassing residues 840-1140 Arabidopsis thaliana protein sequence UniProt:F4JC97-1
-
-
anti-Proteasome (Prosome, Macropain) Activator Subunit 4 (PSME4) (AA 1634-1843) antibody
PSME4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Activator Subunit 4 (PSME4) (AA 105-198) antibodyPSME4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Activator Subunit 4 (PSME4) (AA 503-535) antibodyPSME4 适用: 人 WB 宿主: 兔 Polyclonal RB55279 unconjugated
-
-
应用备注
- 1 : 500 (WB)
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- For reconstitution add 50 μL, of sterile water
-
缓冲液
- Serum
-
注意事项
- Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Store lyophilized/reconstituted at -20°C (short tem, months) or at -80°C (long term, years) , once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
-
-
- PSME4 (Proteasome (Prosome, Macropain) Activator Subunit 4 (PSME4))
-
别名
- PA200
-
背景
- PA200 (Proteasome activator PA200) is an associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during DNA damage response. It also recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. involved in DNA damage response: binds to acetylated histones and promotes degradation of histones. Protein levels increase upon exposure of seedlings to MG132, a specific, potent, reversible, and cell-permeable proteasome inhibitor. Alternative names: Proteasome activator subunit 4, Proteasome activating protein 200.
-
分子量
- 202.9 | ca. 200 kDa
-
基因ID
- 820533
-
UniProt
- F4JC97-1
-
途径
- DNA Replication, Synthesis of DNA
抗原
-
