电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

PSME4 抗体

PSME4 适用: 人, 小鼠, 大鼠 WB, ELISA, IP, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7117899
发货至: 中国
  • 抗原 See all PSME4 抗体
    PSME4 (Proteasome (Prosome, Macropain) Activator Subunit 4 (PSME4))
    适用
    人, 小鼠, 大鼠
    宿主
    • 7
    克隆类型
    • 7
    多克隆
    标记
    • 4
    • 1
    • 1
    • 1
    This PSME4 antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    proteasome(prosome, macropain) activator subunit 4
    亚型
    IgG
    Top Product
    Discover our top product PSME4 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IP: 1:500-1:1000 , IHC: 1:50-1:500, IF: 1:10-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    PSME4 (Proteasome (Prosome, Macropain) Activator Subunit 4 (PSME4))
    别名
    PSME4 (PSME4 产品)
    别名
    proteasome activating protein 200 antibody, Afu4g11290 antibody, An04g05320 antibody, AO090003001091 antibody, PA200 antibody, AA409398 antibody, AU041366 antibody, TEMO antibody, mKIAA0077 antibody, proteasome activator subunit 4 antibody, proteasome activating protein 200 antibody, proteasome (prosome, macropain) activator subunit 4 antibody, PSME4 antibody, Psme4 antibody, PA200 antibody, AFUA_4G11290 antibody, ANI_1_888184 antibody, AOR_1_1944154 antibody, TERG_07227 antibody, psme4 antibody
    背景
    Synonyms:KIAA0077 Background:Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP-and ubiquitin-independent degradation of core histones during spermatogenesis and DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like(BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. Component of the spermatoproteasome, a form of the proteasome specifically found in testis: binds to acetylated histones and promotes degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. Also involved in DNA damage response in somatic cells, by promoting degradation of histones following DNA double-strand breaks.
    分子量
    140 kDa
    基因ID
    23198
    UniProt
    Q14997
    途径
    DNA Replication, Synthesis of DNA
You are here: