TNF alpha 抗体
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北京 101111
Quick Overview for TNF alpha 抗体 (ABIN8063041)
抗原
See all TNF alpha 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Purified Anti-Human TNF-α Antibody[MAb11]
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纯化方法
- >98%, Protein A/G purified
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纯度
- >98 %
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免疫原
- Recombinant Human TNF-alpha protein
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亚型
- IgG1, kappa
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应用备注
- FCM 2 μg/mL(0.5x106-1x106 cells)
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限制
- 仅限研究用
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浓度
- ≥ 1 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.05 % non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
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有效期
- 12 months
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- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
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别名
- TNF-alpha
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背景
- Tumor Necrosis Factor Ligand Superfamily Member,TNFSF,TNF,DIF,TNF-alpha,TNFA,TNFSF2,TNLG1F,TNF alpha,Cachectin,Tumor Necrosis Factor,Tumor Necrosis Factor Ligand Superfamily Member 2,TNF-a,APC1,APC1 protein,DIF,TNF-alpha,TNFA,TNFSF2,Differentiation inducing factor,Macrophage cytotoxic factor,macrophage derived,member 2,Membrane Form,monocyte derived,soluble form,sTNFA,TNF superfamily,Tumor necrosis factor alpha,This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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UniProt
- P01375
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途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
抗原
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