Adenosine A2a Receptor 抗体 (AA 144-410)
Quick Overview for Adenosine A2a Receptor 抗体 (AA 144-410) (ABIN7825254)
抗原
See all Adenosine A2a Receptor (ADORA2A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 144-410
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原理
- Anti-ADORA2A Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-ADORA2A Antibody catalog # A02268-2. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ADORA2A recombinant protein (Position: N144-G410). Human ADORA2A shares 76.8% and 75.3% amino acid (aa) sequence identity with mouse and rat ADORA2A, respectively.
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亚型
- IgG
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anti-Adenosine A2a Receptor (ADORA2A) (C-Term) antibody
ADORA2A 适用: 人 WB 宿主: 山羊 Polyclonal unconjugated
anti-Adenosine A2a Receptor (ADORA2A) (AA 274-412) antibodyADORA2A 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6A6G11 unconjugated
anti-Adenosine A2a Receptor (ADORA2A) antibodyADORA2A 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A2a Receptor (ADORA2A) (AA 1-412) antibodyADORA2A 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Adenosine A2a Receptor (ADORA2A) (AA 165-300) antibodyADORA2A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A2a Receptor (ADORA2A) (AA 291-412) antibodyADORA2A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A2a Receptor (ADORA2A) (AA 347-381), (C-Term) antibodyADORA2A 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB52103 unconjugated
anti-Adenosine A2a Receptor (ADORA2A) (Internal Region) antibodyADORA2A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A2a Receptor (ADORA2A) (AA 1-412) antibodyADORA2A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A2a Receptor (ADORA2A) (AA 147-267) antibodyADORA2A 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4E4 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Adenosine A2a Receptor (ADORA2A)
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别名
- ADORA2A
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背景
- This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding.
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分子量
- 45 kDa
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基因ID
- 135
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UniProt
- P29274
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途径
- Neurotrophin Signaling Pathway, cAMP Metabolic Process, Synaptic Membrane, Feeding Behaviour, Cancer Immune Checkpoints
抗原
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