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TRAF3 抗体 (AA 101-200) (Biotin)

This anti-TRAF3 antibody is a 兔 多克隆 antibody detecting TRAF3 in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 人 和 小鼠.
产品编号 ABIN738923
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TRAF3 抗体 (AA 101-200) (Biotin) (ABIN738923)

抗原

See all TRAF3 抗体
TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

适用

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人, 小鼠

宿主

  • 61
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克隆类型

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多克隆

标记

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This TRAF3 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 101-200

    交叉反应

    人, 小鼠

    预测反应

    Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human TRAF3

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

    别名

    TRAF3

    背景

    Synonyms: CAP1, LAP1, CAP-1, CRAF1, IIAE5, CD40bp, TNF receptor-associated factor 3, CD40 receptor-associated factor 1, CD40-binding protein, LMP1-associated protein 1, TRAF3

    Background: Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon. Required for normal antibody isotype switching from IgM to IgG. Plays a role T-cell dependent immune responses. Plays a role in the regulation of antiviral responses. Is an essential constituent of several E3 ubiquitin-protein ligase complexes. May have E3 ubiquitin-protein ligase activity and promote 'Lys-63'-linked ubiquitination of target proteins. Inhibits activation of NF-kappa-B in response to LTBR stimulation. Inhibits TRAF2-mediated activation of NF-kappa-B. Down-regulates proteolytic processing of NFKB2, and thereby inhibits non-canonical activation of NF-kappa-B. Promotes ubiquitination and proteasomal degradation of MAP3K14.

    基因ID

    7187

    UniProt

    Q13114

    途径

    NF-kappaB Signaling, Apoptosis, TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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