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Recombinant ATM 抗体 (AA 2550-2600)

This 兔 单克隆 antibody specifically detects ATM in WB, IHC, IP 和 ICC. It exhibits reactivity toward 人.
产品编号 ABIN7795796
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant ATM 抗体 (AA 2550-2600) (ABIN7795796)

抗原

See all ATM 抗体
ATM (Ataxia Telangiectasia Mutated (ATM))

抗体类型

Recombinant Antibody

适用

  • 186
  • 79
  • 34
  • 3
  • 1
  • 1

宿主

  • 160
  • 20
  • 5
  • 2

克隆类型

  • 122
  • 65
单克隆

标记

  • 83
  • 11
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
This ATM antibody is un-conjugated

应用范围

  • 111
  • 65
  • 62
  • 51
  • 50
  • 46
  • 40
  • 39
  • 28
  • 26
  • 8
  • 7
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

克隆位点

BLR359N
  • 抗原表位

    • 43
    • 16
    • 15
    • 13
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2550-2600

    原理

    Rabbit anti-ATM Recombinant Monoclonal Antibody [BLR359N]

    纯化方法

    Purified

    免疫原

    between 2550 and 2600

    亚型

    IgG
  • 应用备注

    ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,WB,11,000,IP,6 μL/mg lysate

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1000 μg/mL

    缓冲液

    Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2 - 8 °C

    有效期

    12 months
  • 抗原

    ATM (Ataxia Telangiectasia Mutated (ATM))

    别名

    ATM

    背景

    Ataxia telangiectasia, mutated (ATM) is the gene responsible for the neurodegenerative disease ataxia telangiectasia (AT). AT is characterized by neurodegeneration, immune dysfunction, sensitivity to DNA damage, and cancer predisposition. ATM is a protein kinase central to the DNA damage response. In response to DNA double-strand breaks (DSBs), ATM initiates a signaling cascade that involves the phosphorylation of a multitude of substrates which include p53, BRCA1, p53 binding protein, CHK2, RAD9, RAD17, and MDM4.

    基因ID

    472

    UniProt

    Q13315

    途径

    p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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