IGF1R 抗体
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北京 101111
Quick Overview for IGF1R 抗体 (ABIN7795597)
抗原
See all IGF1R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse anti-IGF1R Monoclonal Antibody [BC10] - BSA-Free
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纯化方法
- Purified
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免疫原
- IGF1R
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1000 μg/mL
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缓冲液
- Phosphate Buffered Saline (PBS) containing 0.09 % Sodium Azide, BSA-Free
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2 - 8 °C
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有效期
- 12 months
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- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
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别名
- IGF1R
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背景
- IGF1R is a receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1) and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. IGF1R is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [taken from NCBI Entrez Gene (Gene ID: 3480)].
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基因ID
- 3480
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UniProt
- P08069
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途径
- RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
抗原
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