IGF1R 抗体
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北京 101111
Quick Overview for IGF1R 抗体 (ABIN7795596)
抗原
See all IGF1R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse anti-IGF1R Monoclonal Antibody [BC10]
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纯化方法
- Purified
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免疫原
- IGF1R
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亚型
- IgG2a
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应用备注
- ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 500 μg/mL
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缓冲液
- Phosphate Buffered Saline (PBS) with 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2 - 8 °C
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有效期
- 12 months
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- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
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别名
- IGF1R
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背景
- IGF1R is a receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1) and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. IGF1R is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [taken from NCBI Entrez Gene (Gene ID: 3480)].
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基因ID
- 3480
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UniProt
- P08069
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途径
- RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
抗原
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