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CD86 抗体 (PE-Cy3)

CD86 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig FACS, WB 宿主: 兔 Polyclonal PE-Cy3
产品编号 ABIN736712
发货至: 中国
  • 抗原 See all CD86 抗体
    CD86
    适用
    • 131
    • 106
    • 49
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    人, 小鼠, 大鼠, 犬, Cow, Pig
    宿主
    • 76
    • 63
    • 59
    克隆类型
    • 137
    • 58
    • 1
    多克隆
    标记
    • 79
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    This CD86 antibody is conjugated to PE-Cy3
    应用范围
    • 135
    • 89
    • 38
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    Flow Cytometry (FACS), Western Blotting (WB)
    交叉反应
    犬, 人, 小鼠, 大鼠
    预测反应
    Cow,Sheep,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from rat CD86
    亚型
    IgG
    Top Product
    Discover our top product CD86 Primary Antibody
  • 应用备注
    FCM(1:100-500)
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    CD86
    别名
    CD86 (CD86 产品)
    别名
    B7-2 antibody, B7.2 antibody, B70 antibody, CD28LG2 antibody, LAB72 antibody, B7 antibody, CLS1 antibody, Cd28l2 antibody, ETC-1 antibody, Ly-58 antibody, Ly58 antibody, MB7 antibody, MB7-2 antibody, TS/A-2 antibody, CD86 molecule antibody, CD86 antigen antibody, integrin subunit alpha 2b antibody, CD86 antibody, Cd86 antibody, Itga2b antibody
    背景

    Synonyms: B7-2, Cd86 antigen, Cd86, Membrane glycoprotein

    Background: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

    基因ID
    56822
    UniProt
    O35531
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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