TGFBR3 抗体 (AA 701-850) (Biotin)
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- 抗原 See all TGFBR3 抗体
- TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))
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抗原表位
- AA 701-850
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TGFBR3 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Sheep,Pig,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human TGFBR3
- 亚型
- IgG
- Top Product
- Discover our top product TGFBR3 Primary Antibody
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anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (AA 147-328) antibody
TGFBR3 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1C5H11 unconjugated
anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (AA 147-328) antibodyTGFBR3 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal 1C5H11 unconjugated
anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (AA 469-724) antibodyTGFBR3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (AA 140-340) antibodyTGFBR3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (AA 285-319) antibodyTGFBR3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB57596 unconjugated
anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (Internal Region) antibodyVerified TGFBR3 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (AA 210-465) antibodyTGFBR3 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (Extracellular Domain) antibodyTGFBR3 适用: 小鸡 WB, IHC 宿主: 绵羊 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (Tyr160) antibodyTGFBR3 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta Receptor III (TGFBR3) (C-Term) antibodyTGFBR3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))
- 别名
- TGF Beta R3 (TGFBR3 产品)
- 别名
- TGFBR3 antibody, DKFZp469I0915 antibody, BGCAN antibody, betaglycan antibody, 1110036H20Rik antibody, AU015626 antibody, AW215636 antibody, TBRIII antibody, transforming growth factor beta receptor 3 antibody, transforming growth factor, beta receptor III antibody, TGFBR3 antibody, tgfbr3 antibody, Tgfbr3 antibody
- 背景
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Synonyms: Beta glycan, Betaglycan, Betaglycan proteoglycan, BGCAN, TGF beta receptor type 3, TGF beta receptor type III, TGF beta Receptor III, TGFB R3, TGFBR 3, TGFBR3, TGFR 3, TGFR3, Transforming Growth Factor Beta Receptor III, Transforming growth factor beta receptor III betaglycan 300 kDa.
Background: Membrane Receptors Transforming growth factor beta is a multifunctional cytokine known to modulate several tissue development and repair processes, including cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production. There are 3 forms encoded by separate genes TGFB1, TGFB2, and TGFB3. The diverse effects of TGF beta are mediated by the TGF beta receptors and cell surface binding proteins. In addition to type I TGF beta receptor (TGFBR1) and type II (TFGBR2), type III (TGF beta III receptor) has been identified. It is a glycoprotein that binds TGF beta and exists in both a membrane bound and a soluble form. It may serve as a receptor accessory molecule in both the TGF beta and fibroblast growth factor systems. TGF beta III receptor lacks a recognizable signaling domain and has no clearly defined role in TGF beta signaling. Endothelial cells undergoing epithelial mesenchymal transformation express TGF beta III receptor, and TGF beta III receptor specific antisera inhibits mesenchyme formation and migration. Misexpression of TGF beta III receptor in nontransforming ventricular endothelial cells conferrs transformation in response to TGFB2. These results support a model where TGF beta III receptor localizes transformation in the heart and plays an essential, nonredundant role in TGF beta signaling. TGF beta III receptor, or beta glycan, can function as an inhibin coreceptor with ActRII. TGF beta III receptor binds inhibin with high affinity and enhances binding in cells coexpressing ActRII and TGF beta III receptor. Inhibin forms crosslinked complexes with both recombinant and endogenously expressed TGF beta III receptor and ActRII. TGF beta III receptor confers inhibin sensitivity to cell lines that otherwise respond poorly to this hormone.
- 基因ID
- 7049
- UniProt
- Q03167
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