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Neuregulin 1 抗体 (AA 221-320) (FITC)

This FITC-conjugated 兔 多克隆 anti-Neuregulin 1 antibody specifically detects Neuregulin 1 in WB, FACS, IF (cc) 和 IF (p). The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN734880
发货至: 中国
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Quick Overview for Neuregulin 1 抗体 (AA 221-320) (FITC) (ABIN734880)

抗原

See all Neuregulin 1 (NRG1) 抗体
Neuregulin 1 (NRG1)

适用

  • 107
  • 73
  • 49
  • 15
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 119
  • 15
  • 1

克隆类型

  • 118
  • 17
多克隆

标记

  • 62
  • 14
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  • 1
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This Neuregulin 1 antibody is conjugated to FITC

应用范围

  • 92
  • 45
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  • 22
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  • 12
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  • 10
  • 7
  • 2
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  • 2
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 16
    • 15
    • 15
    • 9
    • 9
    • 6
    • 6
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    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 221-320

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from mouse Pro-NRG1

    亚型

    IgG
  • 应用备注

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Neuregulin 1 (NRG1)

    别名

    Pro-NRG1

    背景

    Synonyms: GGF, HGL, HRG, NDF, ARIA, GGF2, HRG1, HRGA, SMDF, MST131, MSTP131, NRG1-IT2, Pro-neuregulin-1, membrane-bound isoform, Pro-NRG1, NRG1

    Background: Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells, inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction, stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells, stimulating Schwann cell proliferation, implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.

    基因ID

    211323

    UniProt

    Q6DR98

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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