Ephrin A1 抗体 (AA 101-205)
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北京 101111
Quick Overview for Ephrin A1 抗体 (AA 101-205) (ABIN734108)
抗原
See all Ephrin A1 (EFNA1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-205
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交叉反应
- 人
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预测反应
- Mouse,Rat
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Ephrin A1
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亚型
- IgG
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anti-Ephrin A1 (EFNA1) (AA 19-182) antibody
EFNA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) antibodyEFNA1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) (Internal Region) antibodyEFNA1 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) antibodyEFNA1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Ephrin A1 (EFNA1) (AA 150-164), (Extracellular) antibodyEFNA1 适用: 人 WB, IF, FACS, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) (AA 19-182) antibodyEFNA1 适用: 人 ELISA, WB, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) (AA 19-182) antibodyEFNA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) antibodyEFNA1 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A1 (EFNA1) antibodyKD Validated EFNA1 适用: 人 WB 宿主: 兔 Monoclonal 23GB5265 unconjugated Recombinant Antibody
anti-Ephrin A1 (EFNA1) (Internal Region) antibodyEFNA1 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- Ephrin A1 (EFNA1)
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别名
- Ephrin A1
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背景
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Synonyms: Ephrin-A1, EFNA1, EPH-related receptor tyrosine kinase ligand 1, LERK-1, Immediate early response protein B61, Tumor necrosis factor alpha-induced protein 4, EPLG1, LERK1, TNFAIP4
Background: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Plays an important role in angiogenesis and tumor neovascularization. The recruitment of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. Exerts anti-oncogenic effects in tumor cells through activation and down-regulation of EPHA2. Activates EPHA2 by inducing tyrosine phosphorylation which leads to its internalization and degradation. Acts as a negative regulator in the tumorigenesis of gliomas by down-regulating EPHA2 and FAK. Can evoke collapse of embryonic neuronal growth cone and regulates dendritic spine morphogenesis.
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基因ID
- 1942
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UniProt
- P20827
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途径
- RTK signaling
抗原
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