CD51 抗体 (PE)
Quick Overview for CD51 抗体 (PE) (ABIN7673734)
抗原
See all CD51 (ITGAV) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PE Anti-Mouse CD51 Antibody
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纯化方法
- 0
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纯度
- 0
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亚型
- IgG1, kappa
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应用备注
- Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- 4 °C
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储存方法
- 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- CD51 (ITGAV) (Integrin alpha V (ITGAV))
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别名
- CD51
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背景
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Synonyms: ITGAV|Integrin alpha-V|Integrin αV chain|Vitronectin Receptor|αV integrin
Background: CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6, these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αvintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.
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分子量
- 0
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基因ID
- 16410
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UniProt
- P43406
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途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
抗原
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