AXL 抗体
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北京 101111
Quick Overview for AXL 抗体 (ABIN7670540)
抗原
See all AXL 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Axl Polyclonal Antibody(Capture/Detector)
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纯化方法
- Antigen Affinity Purification
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免疫原
- Recombinant Human Axl protein expressed by Mammalian
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亚型
- IgG
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应用备注
- ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Sterile PBS , pH 7.4
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储存液
- Without preservative
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注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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有效期
- 12 months
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- AXL (AXL Receptor tyrosine Kinase (AXL))
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别名
- Axl
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背景
- AXL,The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.AXL (AXL Receptor Tyrosine Kinase) is a Protein Coding gene. Diseases associated with AXL include Lymphocytic Choriomeningitis and Femoral Neuropathy. Among its related pathways are GPCR Pathway and RET signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is MERTK.
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UniProt
- P30530
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途径
- RTK signaling, Cellular Response to Molecule of Bacterial Origin
抗原
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