CD14 抗体
Quick Overview for CD14 抗体 (ABIN7670148)
抗原
See all CD14 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- AF/LE Purified Anti-Human CD14 Antibody[M5E2]
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内毒素水平
- Low Endotoxin
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亚型
- IgG2a, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- ≥ 1 mg/mL
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缓冲液
- Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.
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储存液
- Azide free
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注意事项
- avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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有效期
- 12 months
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- CD14
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别名
- CD14
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背景
- Monocyte differentiation antigen CD,CD14,soluble,CD14 antigen,CD14 Molecule,monocyte differentiation antigen CD14,Myeloid cell-specific leucine-rich glycoprotein,LPS R,CD 14,CD_antigen=CD14,LPS-R,membrane-bound form,Mo2,Monocyte differentiation antigen CD14 urinary form,Myeloid cell specific leucine rich glycoprotein,The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 14 (CD14) is a member of the CD system. It takes its name from its inclusion in the CD molecule surface marker proteins. CD14 exists in two forms: a form anchored into the membrane or a soluble form. CD14 was found expressed in macrophages, neutrophil granulocyte and dendritic cells. The major function is to serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns.
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UniProt
- P08571
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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