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SPTA1 抗体 (AA 356-475) (Biotin)

This anti-SPTA1 antibody is a 小鼠 单克隆 antibody detecting SPTA1 in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7660119
发货至: 中国

Quick Overview for SPTA1 抗体 (AA 356-475) (Biotin) (ABIN7660119)

抗原

See all SPTA1 抗体
SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

适用

  • 67
  • 13
  • 5
  • 1
  • 1
  • 1
  • 1

宿主

  • 38
  • 30
小鼠

克隆类型

  • 54
  • 14
单克隆

标记

  • 30
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SPTA1 antibody is conjugated to Biotin

应用范围

  • 50
  • 49
  • 39
  • 9
  • 6
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

SPTA1-1810
  • 抗原表位

    • 47
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 356-475

    原理

    Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1810), Biotin conjugate

    产品特性

    Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous i± andi² chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin i± I and spectrini² I are present in erythrocytes, whereas spectrin i± II (also designated fodrin i±) and spectrini² II (also designated fodrini²) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human SPTA fragment (around aa356-475)

    亚型

    IgG2c, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: Jurkat cells. Placenta or Tonsil.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

    别名

    Spectrin Alpha 1

    背景

    Synonyms: Alpha I spectrin, Elliptocytosis 2 (EL2), Erythrocyte alpha spectrin, Erythroid alpha-spectrin, HPP, HS3, Spectrin alpha erythrocytic 1, SPH3, SPTA1

    Gene Symbol: SPTA1

    Tissue Expression: Red blood cells

    分子量

    240 kDa

    基因ID

    6708

    UniProt

    P02549

    途径

    Regulation of Actin Filament Polymerization
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