Recombinant SPTA1 抗体 (AA 356-475) (CF®405S)
Quick Overview for Recombinant SPTA1 抗体 (AA 356-475) (CF®405S) (ABIN7660094)
抗原
See all SPTA1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 356-475
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原理
- Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/2939R), CF405S conjugate
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产品特性
- Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous alpha and beta chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin alpha I and spectrin beta I are present in erythrocytes, whereas spectrin alpha II (also designated fodrin alpha) and spectrin beta II (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment of human SPTA (around aa356-475)
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亚型
- IgG
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anti-Spectrin alpha 1, Erythrocytic (SPTA1) (AA 940-1160) antibody
SPTA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Spectrin alpha 1, Erythrocytic (SPTA1) (AA 356-475) antibodySPTA1 适用: 人 WB, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal SPTA1-1832 unconjugated
anti-Spectrin alpha 1, Erythrocytic (SPTA1) antibodySPTA1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Spectrin alpha 1, Erythrocytic (SPTA1) (AA 356-475) antibodySPTA1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal rSPTA1-1832 unconjugated Recombinant Antibody
anti-Spectrin alpha 1, Erythrocytic (SPTA1) (AA 356-475) antibodySPTA1 适用: 人 WB, IHC, ELISA, Coat, StM 宿主: 兔 Monoclonal SPTA1-2939R unconjugated Recombinant Antibody
anti-Spectrin alpha 1, Erythrocytic (SPTA1) (AA 356-475) antibodySPTA1 适用: 人 IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal SPTA1-1810 unconjugated
anti-Spectrin alpha 1, Erythrocytic (SPTA1) antibodySPTA1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Spectrin alpha 1, Erythrocytic (SPTA1) antibodySPTA1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. ELISA: 2-4 μg/m for coating order Ab without BSA. Immunohistology (formalin): 1-2 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: Jurkat cells. Placenta or Tonsil.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))
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别名
- Spectrin Alpha 1
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背景
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Synonyms: Alpha I spectrin, Elliptocytosis 2 (EL2), Erythrocyte alpha spectrin, Erythroid alpha-spectrin, HPP, HS3, Spectrin alpha erythrocytic 1, SPH3, SPTA1
Gene Symbol: SPTA1
Tissue Expression: Red blood cells
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分子量
- 240 kDa
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基因ID
- 6708
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UniProt
- P02549
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途径
- Regulation of Actin Filament Polymerization
抗原
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