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JNK 抗体 (pThr183, pTyr185) (FITC)

This anti-JNK antibody is a 兔 多克隆 antibody detecting JNK in WB, FACS, IF (cc) 和 IF (p). Suitable for 人, 小鼠, 大鼠, 犬 和 兔. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN732375
发货至: 中国

Quick Overview for JNK 抗体 (pThr183, pTyr185) (FITC) (ABIN732375)

抗原

See all JNK (MAPK8) 抗体
JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

适用

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人, 小鼠, 大鼠, 犬, 兔

宿主

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克隆类型

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多克隆

标记

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This JNK antibody is conjugated to FITC

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    pThr183, pTyr185

    交叉反应

    犬, 人, 小鼠, 兔, 大鼠

    预测反应

    Cow,Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human JNK1 around the phosphorylation site of Thr183/Tyr185

    亚型

    IgG
  • 应用备注

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • Iriyama, Hatta, Takei: "Direct effect of dasatinib on signal transduction pathways associated with a rapid mobilization of cytotoxic lymphocytes." in: Cancer medicine, Vol. 5, Issue 11, pp. 3223-3234, (2016) (PubMed).

  • 抗原

    JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

    别名

    JNK1 , 2 , 3

    背景

    Synonyms: JNK, JNK1, PRKM8, SAPK1, JNK-46, JNK1A2, SAPK1c, JNK21B1/2, Mitogen-activated protein kinase 8, MAP kinase 8, MAPK 8, Stress-activated protein kinase 1c, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1, MAPK8

    Background: JNK1 isoforms display different binding patterns: beta-1 preferentially binds to c-Jun, whereas alpha-1, alpha-2, and beta-2 have a similar low level of binding to both c-Jun or ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms.

    基因ID

    5599

    UniProt

    P45983

    途径

    MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins
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