HGF 抗体
Quick Overview for HGF 抗体 (ABIN7654964)
抗原
See all HGF 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- HGF / SF(EGH2 4C12.1)
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产品特性
- This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human HGF/SF protein.
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亚型
- IgG2b, kappa
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: HGF lysate.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, no BSA, no azide
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at -20 °C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))
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别名
- HGF
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背景
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Synonyms: F-TCF, Fibroblast derived tumor cytotoxic factor, Hepatocyte growth factor (hepapoietin A, scatter factor), Hepatocyte growth factor beta chain, Hepatopoietin-A, HGF, HGFB, HPTA, Lung fibroblast derived mitogen, Scatter Factor
Gene Symbol: HGF
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分子量
- 91/64/34 kDa precursor//
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基因ID
- 3082
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UniProt
- P14210
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途径
- RTK signaling, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
抗原
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