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HGF 抗体 (C-Term)

This 兔多克隆 antibody specifically detects HGF in WB, FACS 和 IHC (p). It exhibits reactivity toward 人. It has been mentioned in 2+ publications

HGF Antibody (C-term) (ABIN388462 and ABIN2848889) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram). (HGF 抗体 (C-Term))

FACS

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with HGF antibody (C-term) (ABIN388462 and ABIN2848889) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (HGF 抗体 (C-Term))

IHC (p)

3 images

(2 references)

产品编号 ABIN388462

发货至: 中国

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Quick Overview for HGF 抗体 (C-Term) (ABIN388462)

抗原

See all HGF 抗体

HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))

适用

人

宿主

兔

克隆类型

多克隆

标记

This HGF antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB09924

Discover our top product HGF Primary Antibody

抗原表位
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AA 521-554, C-Term

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This HGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-554 amino acids from the C-terminal region of human HGF.

亚型

Ig Fraction
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 1-728) antibody
HGF 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (N-Term) antibody
HGF 适用: 人, 大鼠, 小鼠, 犬, 绵羊, 兔, Cow, 马, 豚鼠, Pig, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 521-554) antibody
HGF 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 201-300) antibody
HGF 适用: 人, 大鼠, 小鼠, 绵羊 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 482-710) antibody
HGF 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 306-471) antibody
HGF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 216-265) antibody
HGF 适用: 人, 大鼠, 小鼠, 犬, 兔, Cow, 马, 豚鼠, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 495-728) antibody
HGF 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated

anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 619-728) antibody
HGF 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 33-64), (N-Term) antibody
HGF 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Phan, Fuentes-Mattei, Wu, Velazquez-Torres, Sircar, Wood, Hai, Jimenez, Cote, Ozsari, Hofmann, Zheng, Verhaak, Pagliaro, Cortez, Lee, Yeung, Habra: "Hepatocyte Growth Factor/cMET Pathway Activation Enhances Cancer Hallmarks in Adrenocortical Carcinoma." in: Cancer research, Vol. 75, Issue 19, pp. 4131-42, (2015) (PubMed).

Vogel, Chatterjee, Metzger, Borst, Geisler, Seizer, Müller, Mack, Schumann, Bhring, Lang, Sorg, Langer, Gawaz et al.: "Activated platelets interfere with recruitment of mesenchymal stem cells to apoptotic cardiac cells via high mobility group box 1/Toll-like receptor 4-mediated down-regulation of hepatocyte growth ..." in: The Journal of biological chemistry, Vol. 289, Issue 16, pp. 11068-82, (2014) (PubMed).
抗原

HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))

别名

HGF

背景

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69- kDa alpha-chain and 34- kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. Transcript Variant: This variant (1) encodes the longest isoform (1). To date, experimental evidence for cleavage of the proprotein into two mature chains has been shown only for isoform 1.

分子量

83134

基因ID

3082

NCBI登录号

NP_000592, NP_001010931, NP_001010932, NP_001010933, NP_001010934

UniProt

P14210

途径

RTK signaling, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor