HGF 抗体 (N-Term)
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北京 101111
Quick Overview for HGF 抗体 (N-Term) (ABIN3042443)
抗原
See all HGF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 33-64, N-Term
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原理
- Anti-Hepatocyte growth factor HGF Antibody
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序列
- QKKRRNTLHE FKKSAKTTLT KEDPLLKIKT KK
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Hepatocyte growth factor HGF Antibody (ABIN3042443). Tested in WB applications. This antibody reacts with Mouse. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of mouse HGF, different from the related human sequence by five amino acids, and from the related rat sequence by one amino acid.
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亚型
- IgG
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anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 1-728) antibody
HGF 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (N-Term) antibodyHGF 适用: 人, 大鼠, 小鼠, 犬, 绵羊, 兔, Cow, 马, 豚鼠, Pig, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 521-554) antibodyHGF 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 201-300) antibodyHGF 适用: 人, 大鼠, 小鼠, 绵羊 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 482-710) antibodyHGF 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 306-471) antibodyHGF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 216-265) antibodyHGF 适用: 人, 大鼠, 小鼠, 犬, 兔, Cow, 马, 豚鼠, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 521-554), (C-Term) antibodyHGF 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB09924 unconjugated
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 495-728) antibodyHGF 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 619-728) antibodyHGF 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "MicroRNA-210 promotes angiogenesis in acute myocardial infarction." in: Molecular medicine reports, Vol. 17, Issue 4, pp. 5658-5665, (2018) (PubMed).
: "Expression and tissue distribution of hepatocyte growth factor (HGF) and its receptor (c-Met) in alpacas (Vicugna pacos) skins associated with white and brown coat colors." in: Acta histochemica, (2015) (PubMed).
: "Pro-osteogenic effects of fibrin glue in treatment of avascular necrosis of the femoral head in vivo by hepatocyte growth factor-transgenic mesenchymal stem cells." in: Journal of translational medicine, Vol. 12, pp. 114, (2015) (PubMed).
: "Corticosterone mediates the inhibitory effect of restraint stress on the migration of mesenchymal stem cell to carbon tetrachloride-induced fibrotic liver by downregulating CXCR4/7 expression." in: Stem cells and development, Vol. 24, Issue 5, pp. 587-96, (2015) (PubMed).
: "Telmisartan prevents angiotensin II-induced endothelial dysfunction in rabbit aorta via activating HGF/Met system and PPARγ pathway." in: Fundamental & clinical pharmacology, Vol. 28, Issue 5, pp. 501-11, (2014) (PubMed).
: "Effect of herba centellae on the expression of HGF and MCP-1." in: Experimental and therapeutic medicine, Vol. 6, Issue 2, pp. 427-434, (2013) (PubMed).
: "Isogenic mesenchymal stem cells transplantation improves a rat model of chronic aristolochic acid nephropathy via upregulation of hepatic growth factor and downregulation of transforming growth ..." in: Molecular and cellular biochemistry, Vol. 368, Issue 1-2, pp. 137-45, (2012) (PubMed).
: "Change in hepatocyte growth factor concentration promote mesenchymal stem cell-mediated osteogenic regeneration." in: Journal of cellular and molecular medicine, Vol. 16, Issue 6, pp. 1260-73, (2012) (PubMed).
: "HGF-transgenic MSCs can improve the effects of tissue self-repair in a rabbit model of traumatic osteonecrosis of the femoral head." in: PLoS ONE, Vol. 7, Issue 5, pp. e37503, (2012) (PubMed).
: "Urinary excretion and renal production of hepatocyte growth factor in children with Henoch-Schönlein purpura." in: The Journal of international medical research, Vol. 38, Issue 6, pp. 1933-41, (2011) (PubMed).
: "Treatment of experimental hepatic fibrosis by combinational delivery of urokinase-type plasminogen activator and hepatocyte growth factor genes." in: Liver international : official journal of the International Association for the Study of the Liver, Vol. 25, Issue 4, pp. 796-807, (2005) (PubMed).
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: "MicroRNA-210 promotes angiogenesis in acute myocardial infarction." in: Molecular medicine reports, Vol. 17, Issue 4, pp. 5658-5665, (2018) (PubMed).
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- HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))
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别名
- HGF
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背景
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Synonyms: Hepatocyte growth factor,Hepatopoietin-A,Scatter factor,SF,Hepatocyte growth factor alpha chain,Hepatocyte growth factor beta chain,Hgf,
Background: Hepatocyte growth factor/scatter factor (HGF/SF) is a paracrine cellular growth, motility and morphogenic factor. This gene is mapped to 7q21.11. It is secreted by mesenchymal cells and targets and acts primarily uponepithelial cells and endothelial cells, but also acts on haemopoietic progenitor cells. It has been shown to have a major role in embryonic organ development, specifically in myogenesis, in adult organ regeneration and in wound healing. HGF can regulate cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. HGF also serves as a paracrine mediator to control placental development and growth. HGF was identified as one of the liver sinusoidal endothelial cell-derived paracrine mediators promoting hepatocyte growth.
Sequence Similarities: Belongs to the peptidase S1 family. Plasminogen subfamily.
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分子量
- 34 kDa
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基因ID
- 15234
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UniProt
- Q08048
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途径
- RTK signaling, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
抗原
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