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TARDBP 抗体 (AA 21-120) (Cy7)

This anti-TARDBP antibody is a 兔 多克隆 antibody detecting TARDBP in WB, IF (cc) 和 IF (p). Suitable for 大鼠.
产品编号 ABIN728659
发货至: 中国

Quick Overview for TARDBP 抗体 (AA 21-120) (Cy7) (ABIN728659)

抗原

See all TARDBP 抗体
TARDBP (TAR DNA Binding Protein (TARDBP))

适用

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大鼠

宿主

  • 90
  • 22
  • 1

克隆类型

  • 76
  • 37
多克隆

标记

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This TARDBP antibody is conjugated to Cy7

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 10
    • 8
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Cow,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human TDP-43

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    TARDBP (TAR DNA Binding Protein (TARDBP))

    别名

    TARDBP

    背景

    Synonyms: ALS10, TDP-43, TAR DNA-binding protein 43, TARDBP, TDP43

    Background: DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR.

    基因ID

    23435

    UniProt

    Q13148

    途径

    Positive Regulation of Peptide Hormone Secretion
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