NLRP3 抗体
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北京 101111
Quick Overview for NLRP3 抗体 (ABIN7608013)
抗原
See all NLRP3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-NLRP3 antibody(1B11), Rabbit mAb
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 1-93), (Pyrin Domain) antibody
NLRP3 适用: 人, 小鼠 WB, IHC, IF, IP 宿主: 小鼠 Monoclonal Cryo-2 unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 15-120) antibodyNLRP3 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, IHC (p), FACS, ICC, IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 671-1033) antibodyNLRP3 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (C-Term) antibodyVerified NLRP3 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (C-Term) antibodyNLRP3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (N-Term) antibodyNLRP3 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 12-31), (N-Term) antibodyNLRP3 适用: 人, 小鼠, 大鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 158-207) antibodyNLRP3 适用: 人, 犬, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 30-102) antibodyNLRP3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) antibodyNLRP3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2540 unconjugated Recombinant Antibody
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应用备注
- ELISA 1/5000-10000
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please see Certificate of Analysis for specific instructions of reconstitution.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
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别名
- NLRP3
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背景
- This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data, however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid. [provided by RefSeq, Oct 2008]
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UniProt
- Q96P20
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途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
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