TRADD 抗体 (Cytoplasmic Domain, Cytosolic)
Quick Overview for TRADD 抗体 (Cytoplasmic Domain, Cytosolic) (ABIN7602957)
抗原
See all TRADD 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Cytoplasmic Domain, Cytosolic
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原理
- Anti-TRADD Monoclonal Antibody
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产品特性
- Anti-TRADD Monoclonal Antibody (ABIN7602957). Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human TRADD Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
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亚型
- IgG
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应用备注
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WB 1:500-1:1000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:10 -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
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浓度
- Lot specific
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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- TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
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别名
- TRADD
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背景
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Synonyms: Cytoplasmic aconitate hydratase,Aconitase,4.2.1.3,Citrate hydro-lyase,Ferritin repressor protein,Iron regulatory protein 1,IRP1,Iron-responsive element-binding protein 1,IRE-BP 1,ACO1,IREB1,
Tissue Specificity: Widely expressed.
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分子量
- 70 kDa, 90 kDa
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UniProt
- Q15628
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途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C
抗原
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