ADRB1 抗体 (C-Term)
Quick Overview for ADRB1 抗体 (C-Term) (ABIN7602843)
抗原
See all ADRB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-ADRB1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ADRB1 Antibody Picoband® (ABIN7602843). Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human ADRB1, which shares 81.2% amino acid (aa) sequence identity with mouse and rat ADRB1.
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亚型
- IgG
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anti-Adrenergic, beta-1-, Receptor (ADRB1) (Internal Region) antibody
Verified ADRB1 适用: 人 ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 181-250) antibodyADRB1 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) (Middle Region) antibodyADRB1 适用: 人, 大鼠, 小鼠, 犬, Pig, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 401-477) antibodyADRB1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 150-250) antibodyADRB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) antibodyADRB1 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 200-214), (Extracellular) antibodyADRB1 适用: 大鼠 WB, IHC, FACS, IF, LCI 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 181-250) antibody (FITC)ADRB1 适用: 人, 大鼠, 小鼠 WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal FITC
anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 180-229) antibodyADRB1 适用: 人, 大鼠, 小鼠, 犬, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
1. Bachman, E. S., Dhillon, H., Zhang, C.-Y., Cinti, S., Bianco, A. C., Kobilka, B. K., Lowell, B. B. Beta-AR signaling required for diet-induced thermogenesis and obesity resistance. Science 297: 843-845, 2002. 2. Cagliani, R., Fumagalli, M., Pozzoli, U., Riva, S., Comi, G. P., Torri, F., Macciardi, F., Bresolin, N., Sironi, M. Diverse evolutionary histories for beta-adrenoreceptor genes in humans. Am. J. Hum. Genet. 85: 64-75, 2009. 3. Dionne, I. J., Garant, M. J., Nolan, A. A., Pollin, T. I., Lewis, D. G., Shuldiner, A. R., Poehlman, E. T. Association between obesity and a polymorphism in the beta-1-adrenoceptor gene (gly389arg ADRB1) in Caucasian women. Int. J. Obes. Relat. Metab. Disord. 26: 633-639, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))
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别名
- ADRB1
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背景
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Synonyms: Serine/threonine-protein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1, SGK1, SGK
Tissue Specificity: Expressed in most tissues with highest levels in the pancreas, followed by placenta, kidney and lung. Isoform 2 is strongly expressed in brain and pancreas, weaker in heart, placenta, lung, liver and skeletal muscle.
Background: The beta-1 adrenergic receptor (β1 adrenoceptor), also known as ADRB1, is a beta-adrenergic receptor, and also denotes the human gene encoding it. The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Beta-1 adrenoceptors are predominately located in the heart. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.
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分子量
- 51 kDa
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基因ID
- 153
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UniProt
- P08588
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途径
- cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Brown Fat Cell Differentiation
抗原
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