ADRB1 抗体 (Middle Region)
(2 references)-
- 抗原 See all ADRB1 抗体
- ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))
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抗原表位
- Middle Region
- 适用
- 人, 小鼠, 大鼠, 犬, Pig, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ADRB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- CTVWAISALV SFLPILMHWW RAESDEARRC YNDPKCCDFV TNRAYAIASS
- 预测反应
- Dog: 87%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against ADRB1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ADRB1
- Top Product
- Discover our top product ADRB1 Primary Antibody
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anti-Adrenergic, beta-1-, Receptor (ADRB1) (Internal Region) antibody
Verified ADRB1 适用: 人 ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 181-250) antibodyADRB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 401-477) antibodyADRB1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 150-250) antibodyADRB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) antibodyADRB1 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) (2nd Extracellular Loop), (AA 200-214) antibodyADRB1 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 181-250) antibody (FITC)ADRB1 适用: 人, 小鼠, 大鼠 WB, IF (cc), IF (p), FACS 宿主: 兔 Polyclonal FITC
anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 180-229) antibodyADRB1 适用: 人, 小鼠, 大鼠, 犬, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 477 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Propranolol sensitizes thyroid cancer cells to cytotoxic effect of vemurafenib." in: Oncology reports, Vol. 36, Issue 3, pp. 1576-84, (2016) (PubMed).
: "Testosterone replacement increases aged pulmonary vein and left atrium arrhythmogenesis with enhanced adrenergic activity." in: International journal of cardiology, Vol. 176, Issue 1, pp. 110-8, (2014) (PubMed).
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: "Propranolol sensitizes thyroid cancer cells to cytotoxic effect of vemurafenib." in: Oncology reports, Vol. 36, Issue 3, pp. 1576-84, (2016) (PubMed).
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- 抗原
- ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))
- 别名
- ADRB1 (ADRB1 产品)
- 别名
- ADRB1R antibody, B1AR antibody, BETA1AR antibody, RHR antibody, RATB1AR antibody, X-Beta1AR antibody, BAR1 antibody, zgc:194728 antibody, zgc:194731 antibody, ADRB1 antibody, Adrb-1 antibody, beta-AR antibody, adrenoceptor beta 1 antibody, adrenoceptor beta 1 L homeolog antibody, adrenergic, beta-1-, receptor antibody, adrenergic receptor, beta 1 antibody, ADRB1 antibody, Adrb1 antibody, adrb1.L antibody, adrb1 antibody
- 背景
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The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in ADRB1 gene have been shown to affect the resting heart rate and can be involved in heart failure.The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ADRB1R, B1AR, BETA1AR, RHR
Protein Interaction Partner: GPRASP1, GPRASP2, SNTA1, ARRB2, ARRB1, MAGI2, DLG4, GRB2, ADRA2A, MAGI3, DLGAP2, GOPC, GIPC1, SH3GL2, SH3GL3, DLG1, NOS1,
Protein Size: 477 - 分子量
- 51 kDa
- 基因ID
- 153
- NCBI登录号
- NM_000684, NP_000675
- UniProt
- P08588
- 途径
- cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Brown Fat Cell Differentiation
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