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SIN3A 抗体 (AA 8-918)

This anti-SIN3A antibody is a 兔 多克隆 antibody detecting SIN3A in WB, ELISA, IF, IHC, ICC 和 FACS. Suitable for 人 和 大鼠.
产品编号 ABIN7602504
发货至: 中国

Quick Overview for SIN3A 抗体 (AA 8-918) (ABIN7602504)

抗原

See all SIN3A 抗体
SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This SIN3A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • 抗原表位

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    AA 8-918

    原理

    Anti-mSin3A/SIN3A Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-mSin3A/SIN3A Antibody Picoband® (ABIN7602504). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human mSin3A/SIN3A recombinant protein (Position: Q8-E918).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Ayer, D. E., Lawrence, Q. A., Eisenman, R. N. Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3. Cell 80: 767-776, 1995. 2. Balasubramanian, M., Dingemans, A. J. M., Albaba, S., Richardson, R., Yates, T. M., Cox, H., Douzgou, S., Armstrong, R., Sansbury, F. H., Burke, K. B., Fry, A. E., Ragge, N., and 27 others. Comprehensive study of 28 individuals with SIN3A-related disorder underscoring the associated mild cognitive and distinctive facial phenotype. Europ. J. Hum. Genet. 29: 625-636, 2021. 3. Duong, H. A., Robles, M. S., Knutti, D., Weitz, C. J. A molecular mechanism for circadian clock negative feedback. Science 332: 1436-1439, 2011.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

    别名

    SIN3A

    背景

    Synonyms: Microtubule-associated protein 2, MAP-2, MAP2

    Background: Paired amphipathic helix protein Sin3a is a protein that in humans is encoded by the SIN3A gene. The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex.

    分子量

    150 kDa

    基因ID

    25942

    途径

    Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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