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Recombinant SIN3A 抗体

SIN3A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Monoclonal 10G3 unconjugated Recombinant Antibody
产品编号 ABIN7127630
发货至: 中国
  • 抗原 See all SIN3A 抗体
    SIN3A (SIN3 homolog A, transcription regulator (SIN3A))
    抗体类型
    Recombinant Antibody
    适用
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    宿主
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    克隆类型
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    单克隆
    标记
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    This SIN3A antibody is un-conjugated
    应用范围
    • 36
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human mSin3A
    克隆位点
    10G3
    亚型
    IgG
    Top Product
    Discover our top product SIN3A Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SIN3A (SIN3 homolog A, transcription regulator (SIN3A))
    别名
    SIN3A (SIN3A 产品)
    别名
    AW553200 antibody, Sin3 antibody, mKIAA4126 antibody, mSin3A antibody, zgc:162128 antibody, SIN3A antibody, SIN3 transcription regulator family member A antibody, transcriptional regulator, SIN3A (yeast) antibody, paired amphipathic helix protein Sin3a antibody, SIN3 transcription regulator family member Aa antibody, SIN3A antibody, Sin3a antibody, LOC100641919 antibody, sin3aa antibody, LOC100439524 antibody
    背景

    Background: Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in he control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression (By similarity).

    Aliases: Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a), SIN3A

    UniProt
    Q96ST3
    途径
    Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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