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SIN3A 抗体 (N-Term)

There is 1 publication for this product available. The 兔 多克隆 anti-SIN3A antibody is suitable to detect SIN3A in samples from 人 和 小鼠. It has been validated for WB 和 ChIP.
产品编号 ABIN2668357
发货至: 中国
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Quick Overview for SIN3A 抗体 (N-Term) (ABIN2668357)

抗原

See all SIN3A 抗体
SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This SIN3A antibody is un-conjugated

应用范围

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Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
  • 抗原表位

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    N-Term

    原理

    SIN3A antibody (pAb)

    纯化方法

    Unpurified

    免疫原

    This SIN3A antibody was raised against a peptide derived from the N-terminus of human SIN3A.
  • 应用备注

    ChIP: 5 - 10 µL per ChIP WB*: 1:1,000 - 1:5,000 dilution *Note: many chromatin-bound proteins are not soluble in a low salt nuclear extract and fractionate to the pellet. Therefore, we recommend a High Salt / Sonication Protocol when preparing nuclear extracts for Western Blot.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • Chalei, Sansom, Kong, Lee, Montiel, Vance, Ponting: "The long non-coding RNA Dali is an epigenetic regulator of neural differentiation." in: eLife, Vol. 3, pp. e04530, (2014) (PubMed).

  • 抗原

    SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

    别名

    SIN3A

    背景

    SIN3A (Switch independent 3 homologue) is the mammalian homologue of the yeast protein Sin3. SIN3A is transcriptional co-repressor that is recruited to promoters by sequence-specific DNA binding proteins, such as REST, MXI1 and MAD-MAX. It is part of a large multi-subunit repressor protein complex that also contains HDAC1, HDAC2 and SMRT/NCoR1.

    分子量

    155 kDa

    基因ID

    25942

    NCBI登录号

    NP_001138829

    途径

    Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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