SIN3A 抗体 (N-Term)
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Quick Overview for SIN3A 抗体 (N-Term) (ABIN2668357)
抗原
See all SIN3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- SIN3A antibody (pAb)
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纯化方法
- Unpurified
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免疫原
- This SIN3A antibody was raised against a peptide derived from the N-terminus of human SIN3A.
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应用备注
- ChIP: 5 - 10 µL per ChIP WB*: 1:1,000 - 1:5,000 dilution *Note: many chromatin-bound proteins are not soluble in a low salt nuclear extract and fractionate to the pellet. Therefore, we recommend a High Salt / Sonication Protocol when preparing nuclear extracts for Western Blot.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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: "The long non-coding RNA Dali is an epigenetic regulator of neural differentiation." in: eLife, Vol. 3, pp. e04530, (2014) (PubMed).
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- SIN3A (SIN3 homolog A, transcription regulator (SIN3A))
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别名
- SIN3A
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背景
- SIN3A (Switch independent 3 homologue) is the mammalian homologue of the yeast protein Sin3. SIN3A is transcriptional co-repressor that is recruited to promoters by sequence-specific DNA binding proteins, such as REST, MXI1 and MAD-MAX. It is part of a large multi-subunit repressor protein complex that also contains HDAC1, HDAC2 and SMRT/NCoR1.
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分子量
- 155 kDa
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基因ID
- 25942
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NCBI登录号
- NP_001138829
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途径
- Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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