HBEGF 抗体 (AA 63-148)
Quick Overview for HBEGF 抗体 (AA 63-148) (ABIN7602202)
抗原
See all HBEGF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 63-148
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原理
- Anti-Hbegf Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Hbegf Antibody Picoband® (ABIN7602202). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Hbegf recombinant protein (Position: D63-L148).
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亚型
- IgG
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anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 51-150) antibody
HBEGF 适用: 人, 小鼠, 大鼠 ELISA, IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 21-160) antibodyHBEGF 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (EGF Like Domain) antibody (Biotin)HBEGF 适用: 人 WB, ELISA, IP, ICC, IF 宿主: 小鼠 Monoclonal 4G10 Biotin
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (Bound), (EGF Like Domain), (Soluble) antibodyHBEGF 适用: 人 WB, ELISA, IP, ICC, IF 宿主: 小鼠 Monoclonal 4G10 unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 63-148) antibodyHBEGF 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 21-160) antibodyHBEGF 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D2 unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (N-Term) antibodyHBEGF 适用: 人, 小鼠, 大鼠, Cow, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) antibodyHBEGF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) antibodyHBEGF 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Bollee, G., Flamant, M., Schordan, S., Fligny, C., Rumpel, E., Milon, M., Schordan, E., Sabaa, N., Vandermeersch, S., Galaup, A., Rodenas, A., Casal, I., and 14 others. Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis. Nature Med. 17: 1242-1250, 2011. Note: Erratum: Nature Med. 17: 1521 only, 2011. 2. Chang, T.-M., Neville, D. M., Jr. Demonstration of diphtheria toxin receptors on surface membranes from both toxin-sensitive and toxin-resistant species. J. Biol. Chem. 253: 6866-6871, 1978. 3. Creagan, R. P., Chen, S.-H., Ruddle, F. H. Genetic analysis of the cell surface: association of human chromosome 5 with sensitivity to diphtheria toxin in mouse-human somatic cell hybrids. Proc. Nat. Acad. Sci. 72: 2237-2241, 1975. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
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别名
- Hbegf
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背景
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Synonyms: N6-adenosine-methyltransferase catalytic subunit
Tissue Specificity: Widely expressed at low level. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes.
Background: Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of proteins that in humans is encoded by the HBEGF gene. Enables epidermal growth factor receptor binding activity, growth factor activity, and heparin binding activity. Involved in positive regulation of keratinocyte migration, positive regulation of smooth muscle cell proliferation, and wound healing, spreading of epidermal cells. Acts upstream of or within several processes, including epidermal growth factor receptor signaling pathway, positive regulation of peptidyl-tyrosine phosphorylation, and regulation of heart contraction. Located in extracellular space. Is integral component of plasma membrane. Is expressed in several structures, including branchial arch, heart, oral region gland, telencephalon, and tooth. Human ortholog(s) of this gene implicated in glomerulosclerosis and perinatal necrotizing enterocolitis. Orthologous to human HBEGF (heparin binding EGF like growth factor).
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分子量
- 20 kDa
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基因ID
- 15200
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UniProt
- Q06186
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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