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HBEGF 抗体 (AA 51-150)

HBEGF 适用: 人, 小鼠, 大鼠 ELISA, IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN701050
发货至: 中国
  • 抗原 See all HBEGF 抗体
    HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
    抗原表位
    • 15
    • 14
    • 14
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    适用
    • 74
    • 19
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 67
    • 10
    克隆类型
    • 65
    • 11
    • 1
    多克隆
    标记
    • 25
    • 10
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This HBEGF antibody is un-conjugated
    应用范围
    • 34
    • 28
    • 25
    • 14
    • 13
    • 11
    • 8
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human HB-EGF/DTSF
    亚型
    IgG
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Lebkuechner, Wilhelmsson, Möllerström, Pekna, Pekny: "Heterogeneity of Notch signaling in astrocytes and the effects of GFAP and vimentin deficiency." in: Journal of neurochemistry, (2015) (PubMed).

  • 抗原
    HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
    别名
    HB-EGF (HBEGF 产品)
    别名
    hbegf antibody, zgc:165443 antibody, HBEGF antibody, zgc:175091 antibody, DTR antibody, DTS antibody, DTSF antibody, HEGFL antibody, Dtr antibody, GFHB antibody, Hb-egf antibody, Hegfl antibody, AW047313 antibody, Dts antibody, HB-EGF antibody, heparin-binding EGF-like growth factor b antibody, heparin binding EGF like growth factor antibody, Heparin-binding EGF-like growth factor antibody, heparin-binding EGF-like growth factor a antibody, heparin-binding EGF-like growth factor antibody, hbegfb antibody, HBEGF antibody, hbegf antibody, hbegfa antibody, Hbegf antibody
    背景

    Synonyms: DTR, DTS, DTSF, HEGFL, Proheparin-binding EGF-like growth factor, HBEGF

    Background: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

    基因ID
    1839
    UniProt
    Q99075
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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