ROCK1 抗体 (AA 601-833)
Quick Overview for ROCK1 抗体 (AA 601-833) (ABIN7602158)
抗原
See all ROCK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 601-833
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原理
- Anti-ROCK1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ROCK1 Antibody Picoband® (ABIN7602158). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ROCK1 recombinant protein (Position: K601-R833).
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亚型
- IgG
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anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (N-Term) antibody
KO Validated ROCK1 适用: 人 WB, IP, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 1001-1200) antibodyROCK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 401-510) antibodyROCK1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E2 unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (pSer456), (pThr455) antibodyROCK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 400-660) antibodyROCK1 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) antibodyROCK1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1H4 unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 405-668) antibodyROCK1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 1094-1323) antibodyROCK1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) antibodyROCK1 适用: 人, 小鼠, 大鼠 WB, IHC, IP, IF, FACS, ICC 宿主: 兔 Monoclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 1114-1126) antibodyROCK1 适用: 人, 小鼠, 大鼠, 猴, Cow, Bat, 犬, 马 WB 宿主: 小鼠 Monoclonal 154C1465 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Monkey, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Anderson, S. C., SundarRaj, N. Regulation of a Rho-associated kinase expression during the corneal epithelial cell cycle. Invest. Ophthal. Vis. Sci. 42: 933-940, 2001. 2. Bito, H., Furuyashiki, T., Ishihara, H., Shibasaki, Y., Ohashi, K., Mizuno, K., Maekawa, M., Ishizaki, T., Narumiya, S. A critical role for a Rho-associated kinase, p160ROCK, in determining axon outgrowth in mammalian CNS neurons. Neuron 26: 431-441, 2000. 3. Bivalacqua, T. J., Champion, H. C., Usta, M. F., Cellek, S., Chitaley, K., Webb, R. C., Lewis, R. L., Mills, T. M., Hellstrom, W. J. G., Kadowitz, P. J. RhoA/Rho-kinase suppresses endothelial nitric oxide synthase in the penis: a mechanism for diabetes-associated erectile dysfunction. Proc. Nat. Acad. Sci. 101: 9121-9126, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
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别名
- ROCK1
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背景
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Synonyms: Ornithine carbamoyltransferase, mitochondrial,2.1.3.3,Ornithine transcarbamylase,OTCase,OTC,
Tissue Specificity: Mainly expressed in liver and intestinal mucosa.
Background: This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18.
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分子量
- 160 kDa
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基因ID
- 6093
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UniProt
- Q13464
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途径
- Microtubule Dynamics, WNT signaling, M Phase, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling
抗原
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