EPH Receptor A3 抗体 (AA 59-514)
Quick Overview for EPH Receptor A3 抗体 (AA 59-514) (ABIN7602102)
抗原
See all EPH Receptor A3 (EPHA3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 59-514
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原理
- Anti-Eph receptor A3/EPHA3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Eph receptor A3/EPHA3 Antibody Picoband® (ABIN7602102). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Eph receptor A3/EPHA3 recombinant protein (Position: D59-A514).
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亚型
- IgG
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anti-EPH Receptor A3 (EPHA3) (AA 202-326) antibody
EPHA3 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3A12 unconjugated
anti-EPH Receptor A3 (EPHA3) (AA 896-928) antibodyEPHA3 适用: 人, Hamster WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A3 (EPHA3) (AA 202-326) antibodyEPHA3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E9 unconjugated
anti-EPH Receptor A3 (EPHA3) (AA 896-928), (C-Term) antibodyEPHA3 适用: 人, Hamster WB, IHC (p) 宿主: 兔 Polyclonal RB1585 unconjugated
anti-EPH Receptor A3 (EPHA3) (AA 488-500), (Extracellular) antibodyEPHA3 适用: 人 WB, IHC, FACS, IF, LCI 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A3 (EPHA3) (C-Term) antibodyEPHA3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A3 (EPHA3) (AA 38-375) antibodyEPHA3 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A3 (EPHA3) (AA 751-983) antibodyEPHA3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 6C1B6 unconjugated
anti-EPH Receptor A3 (EPHA3) (AA 115-144) antibodyEPHA3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A3 (EPHA3) (AA 401-500) antibodyEPHA3 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Boyd, A. W., Ward, L. D., Wicks, I. P., Simpson, R. J., Salvaris, E., Wilks, A., Welch, K., Loudovaris, M., Rockman, S., Busmanis, I. Isolation and characterization of a novel receptor-type protein tyrosine kinase (hek) from a human pre-B cell line. J. Biol. Chem. 267: 3262-3267, 1992. 2. Fox, G. M., Holst, P. L., Chute, H. T., Lindberg, R. A., Janssen, A. M., Basu, R., Welcher, A. A. cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases. Oncogene 10: 897-905, 1995. 3. Gallarda, B. W., Bonanomi, D., Mueller, D., Brown, A., Alaynick, W. A., Andrews S. E., Lemke, G., Pfaff, S. L., Marquardt, T. Segregation of axial motor and sensory pathways via heterotypic trans-axonal signaling. Science 320: 233-236, 2008. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- EPH Receptor A3 (EPHA3)
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别名
- EPHA3
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背景
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Synonyms: Tumor necrosis factor receptor superfamily member 13C, B-cell maturation defect, B-cell-activating factor receptor, BAFF receptor, BAFF-R, BLyS receptor 3, CD268, Tnfrsf13c, Baffr, Bcmd, Br3
Tissue Specificity: Highly expressed in spleen and testis, detected at lower levels in lung and thymus.
Background: Ephrin Receptor EphA3, is also known as human embryo kinase(HEK) or Eph-like tyrosine kinase1(ETK1). Kinases that phosphorylate proteins on tyrosine residues(protein tyrosine kinases, PTKs), such as EPHA3, form a structurally related group of molecules that exhibit functional diversity. Genetic alterations that lead to the inappropriate activation or expression of PTKs may be oncogenic. Many growth factor receptors are PTKs, e.g., the receptors for epidermal growth factor(EGFR), platelet-derived growth factor(PDGFR1,PDGFR2), colony-stimulating factor-1(CSF1R), and stem cell growth factor. The EPHA3 gene is mapped to 3p11.2. Sequence comparison with other PTKs showed a high degree of homology with members of the EPH and ELK(EPHB1) families of receptor tyrosine kinases. Within axial nerves, establishment of discrete afferent and efferent pathways depends on coordinate signaling between coextending sensory and motor projections.
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分子量
- 135 kDa
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基因ID
- 2042
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UniProt
- P29320
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途径
- RTK signaling, Regulation of Cell Size
抗原
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