MYBL2 抗体 (AA 31-695)
Quick Overview for MYBL2 抗体 (AA 31-695) (ABIN7601277)
抗原
See all MYBL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-695
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原理
- Anti-B MyB/MYBL2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-B MyB/MYBL2 Antibody Picoband® (ABIN7601277). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human B MyB/MYBL2 recombinant protein (Position: K31-R695).
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亚型
- IgG
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anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (AA 1-17), (N-Term) antibody
MYBL2 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (N-Term) antibodyMYBL2 适用: 人, 大鼠, 小鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (AA 601-700) antibodyMYBL2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C7 unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (N-Term) antibodyMYBL2 适用: 人, 大鼠, 犬, Cow, 豚鼠, 马, 猴, 小鸡, 斑马鱼 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (AA 1-700) antibodyMYBL2 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (AA 101-200) antibodyMYBL2 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (AA 540-571) antibodyMYBL2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53927 unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (AA 188-366) antibodyMYBL2 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (AA 601-700) antibodyMYBL2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) antibodyMYBL2 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal MYBAD10A unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Barletta, C., Druck, T., LaForgia, S., Calabretta, B., Drabkin, H., Patterson, D., Croce, C. M., Huebner, K. Chromosome locations of the MYB related genes, AMYB and BMYB. Cancer Res. 51: 3821-3824, 1991. 2. Noben-Trauth, K., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Sonoda, G., Testa, J. R., Klempnauer, K.-H. Mybl2 (Bmyb) maps to mouse chromosome 2 and human chromosome 20q13.1. Genomics 35: 610-612, 1996. 3. Shepard, J. L., Amatruda, J. F., Stern, H. M., Subramanian, A., Finkelstein, D., Ziai, J., Finley, K. R., Pfaff, K. L., Hersey, C., Zhou, Y., Barut, B., Freedman, M., and 9 others. A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility. Proc. Nat. Acad. Sci. 102: 13194-13199, 2005. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))
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别名
- MYBL2
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背景
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Synonyms: Disintegrin and metalloproteinase domain-containing protein 15, ADAM 15, Metalloprotease RGD disintegrin protein, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15, MDC-15, Metargidin, ADAM15, MDC15
Tissue Specificity: Expressed in colon and small intestine. Expressed in airway smooth muscle and glomerular mesangial cells (at protein level). Ubiquitously expressed. Overexpressed in atherosclerotic lesions. Constitutively expressed in cultured endothelium and smooth muscle. Expressed in chondrocytes. Expressed in airway smooth muscle and glomerular mesangial cells.
Background: MYBL2 (V-MYB avian myeloblastosis viral oncogene homolog-like 2), also called MYB-RELATED GENE BMYB, is a protein that in humans is encoded by the MYBL2 gene. The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. Barletta et al. (1991) assigned the MYBL2 gene to chromosome Xq13. However, Noben-Trauth et al. (1996) demonstrated that this assignment was an error. Using mouse Mybl2 cDNA clones as probes, they assigned Mybl2 in an interspecific backcross panel to distal mouse chromosome 2. Using human cDNA probes in combination with fluorescence in situ hybridization analysis, they localized MYBL2 to chromosome 20q13.1, a region that is commonly deleted in myeloid disorders and shows high homology of synteny to mouse chromosome 2. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.
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分子量
- 100 kDa
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基因ID
- 4605
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UniProt
- P10244
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, Chromatin Binding
抗原
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