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MYBL2 抗体 (N-Term)

MYBL2 适用: 人, 大鼠, 小鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029533
发货至: 中国
  • 抗原 See all MYBL2 抗体
    MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))
    抗原表位
    • 20
    • 15
    • 15
    • 7
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 92
    • 39
    • 37
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    人, 大鼠, 小鼠
    宿主
    • 87
    • 5
    • 1
    克隆类型
    • 89
    • 4
    多克隆
    标记
    • 40
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    This MYBL2 antibody is un-conjugated
    应用范围
    • 43
    • 39
    • 39
    • 28
    • 14
    • 14
    • 9
    • 9
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    纯化方法
    Antigen affinity
    免疫原
    An amino acid sequence from the N-terminus of human MYBL2/B-MYB (MSRRTRCEDLDELHYQD) was used as the immunogen for this MYBL2 antibody (100% mouse homology).
    亚型
    IgG
  • 应用备注
    The stated application concentrations are suggested starting amounts. Titration of the MYBL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the MYBL2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))
    别名
    MYBL2 (MYBL2 产品)
    别名
    MYBL2 antibody, bmyb antibody, b-myb antibody, B-Myb antibody, Bmyb antibody, B-MYB antibody, BMYB antibody, myb1 antibody, MYB proto-oncogene like 2 antibody, v-myb avian myeloblastosis viral oncogene homolog-like 2b antibody, myeloblastosis oncogene-like 2 antibody, MYB proto-oncogene like 2 S homeolog antibody, MYBL2 antibody, mybl2 antibody, mybl2b antibody, Mybl2 antibody, mybl2.S antibody
    背景
    V-MYB avian myeloblastosis viral oncogene homolog-like 2, also called MYB-related gene B-MYB, is a protein that in humans is encoded by the MYBL2 gene. The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. Barletta et al.(1991) assigned the gene to chromosome Xq13. However, Noben-Trauth et al.(1996) demonstrated that this assignment was an error. Using mouse Mybl2 cDNA clones as probes, they assigned the gene in an interspecific backcross panel to distal mouse chromosome 2. Using human cDNA probes in combination with fluorescence in situ hybridization analysis, they localized MYBL2 to chromosome 20q13.1, a region that is commonly deleted in myeloid disorders and shows high homology of Synteny to mouse chromosome 2. It has been shown to activate the cell division cycle 2, Cyclin D1, and Insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.
    UniProt
    P10244
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases, Chromatin Binding
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