Connexin 43/GJA1 抗体 (AA 3-362)
Quick Overview for Connexin 43/GJA1 抗体 (AA 3-362) (ABIN7601189)
抗原
See all Connexin 43/GJA1 (GJA1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3-362
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原理
- Anti-Connexin 43/GJA1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Connexin 43/GJA1 Antibody Picoband® (ABIN7601189). Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Connexin 43/GJA1 recombinant protein (Position: D3-R362).
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亚型
- IgG
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anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (C-Term) antibody
GJA1 适用: 人, 大鼠, 小鼠, 犬, Cow, 猴, 兔, 小鸡, 豚鼠, Pig, 马, 绵羊, Hamster, 山羊, 驴, Avian, Cat WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (pSer368) antibodyGJA1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 107-138) antibodyGJA1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 351-367) antibodyGJA1 适用: 人, 大鼠, 小鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 211-260) antibodyGJA1 适用: 人, 大鼠, 小鼠, 犬 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 244-382) antibodyGJA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 233-382) antibodyGJA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (C-Term) antibodyGJA1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 233-382) antibodyGJA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (N-Term) antibodyGJA1 适用: 人, 大鼠, 小鼠, 犬, Cow, 兔, 豚鼠, 斑马鱼, 马, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Britz-Cunningham, S. H., Shah, M. M., Zuppan, C. W., Fletcher, W. H. : Mutations of the connexin43 gap-junction gene in patients with heart malformations and defects of laterality. New Eng. J. Med. 332: 1323-1329, 1995. 2. Liu, X. Z., Xia, X. J., Adams, J., Chen, Z. Y., Welch, K. O., Tekin, M., Ouyang, X. M., Kristiansen, A., Pandya, A., Balkany, T., Arnos, K. S., Nance, W. E. : Mutations in GJA1 (connexin 43) are associated with non-syndromic autosomal recessive deafness. Hum. Molec. Genet. 10: 2945-2951, 2001. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
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别名
- GJA1
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背景
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Synonyms: Gap junction alpha-1 protein, Connexin-43, Cx43, Gap junction 43 kDa heart protein, GJA1, GJAL
Tissue Specificity: Expressed in the heart and fetal cochlea.
Background: Connexin 43 (Cx43), also called GAP Junction Protein, alpha-1 (GJA1). Connexin 43 is a member of the connexin gene family which abundantly expressed in the heart and liver and was mapped to 6q21-q23.2. Connexin43, the major protein of gap junctions in the heart, is targeted by several protein kinases that regulate myocardial cell-cell coupling. Mutations in the connexin43 gap-junction gene, which lead to abnormally regulated cell-cell communication, are associated with visceroatrial heterotaxia. Cx43 must also play a critical role in the physiology of hearing, presumably by participating in the recycling of potassium to the cochlear endolymph.
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分子量
- 43 kDa
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基因ID
- 2697
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UniProt
- P17302
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途径
- MAPK Pathway, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
抗原
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