Girdin 抗体 (AA 1231-1836)
Quick Overview for Girdin 抗体 (AA 1231-1836) (ABIN7599868)
抗原
See all Girdin (CCDC88A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1231-1836
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原理
- Anti-CCDC88A Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-CCDC88A Antibody Picoband® (ABIN7599868). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CCDC88A recombinant protein (Position: K1231-D1836).
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亚型
- IgG
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anti-Coiled-Coil Domain Containing 88A (CCDC88A) (AA 1401-1500) antibody
CCDC88A 适用: 人 ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) antibodyCCDC88A 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) antibodyCCDC88A 适用: 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) (pTyr1765) antibodyCCDC88A 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) (pSer417) antibodyCCDC88A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) (AA 1571-1870) antibodyCCDC88A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Anai, M., Shojima, N., Katagiri, H., Ogihara, T., Sakoda, H., Onishi, Y., Ono, H., Fujishiro, M., Fukushima, Y., Horike, N., Viana, A., Kikuchi, M., Noguchi, N., Takahashi, S., Takata, K., Oka, Y., Uchijima, Y., Kurihara, H., Asano, T. A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis. J. Biol. Chem. 280: 18525-18535, 2005. 2. Enomoto, A., Asai, N., Namba, T., Wang, Y., Kato, T., Tanaka, M., Tatsumi, H., Taya, S., Tsuboi, D., Kuroda, K., Kaneko, N., Sawamoto, K., Miyamoto, R., Jijiwa, M., Murakumo, Y., Sokabe, M., Seki, T., Kaibuchi, K., Takahashi, M. Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus. Neuron 63: 774-787, 2009. 3. Enomoto, A., Murakami, H., Asai, N., Morone, N., Watanabe, T., Kawai, K., Murakumo, Y., Usukura, J., Kaibuchi, K., Takahashi, M. Akt/PKB regulates actin organization and cell motility via Girdin/APE. Dev. Cell. 9: 389-402, 2005. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))
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别名
- CCDC88A
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背景
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Synonyms: CD48 antigen,B-lymphocyte activation marker BLAST-1,BCM1 surface antigen,Leukocyte antigen MEM-102,SLAM family member 2,SLAMF2,Signaling lymphocytic activation molecule 2,TCT.1,CD48,CD48,BCM1, BLAST1,
Background: Girdin is a protein that in humans is encoded by the CCDC88A gene. This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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分子量
- 240 kDa
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基因ID
- 55704
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UniProt
- Q3V6T2
抗原
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