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Girdin 抗体 (pSer1417)

CCDC88A 适用: 人 ELISA, WB, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386096
发货至: 中国
  • 抗原 See all Girdin (CCDC88A) 抗体
    Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))
    抗原表位
    • 26
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer1417
    适用
    • 55
    • 17
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 56
    克隆类型
    • 55
    • 1
    多克隆
    标记
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Girdin antibody is un-conjugated
    应用范围
    • 35
    • 17
    • 14
    • 14
    • 13
    • 8
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Flow Cytometry (FACS)
    交叉反应
    预测反应
    Mouse,Rat,Dog,Cow,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human Girdin around the phosphorylation site of Ser1417
    亚型
    IgG
    Top Product
    Discover our top product CCDC88A Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))
    别名
    Girdin (CCDC88A 产品)
    别名
    APE antibody, GIRDIN antibody, GIV antibody, GRDN antibody, HkRP1 antibody, KIAA1212 antibody, A430106J12Rik antibody, AI848406 antibody, Ape antibody, C130096N06Rik antibody, C330012F17Rik antibody, D130005J21Rik antibody, Girdin antibody, Giv antibody, Grdn antibody, Hkrp1 antibody, DKFZp459N1815 antibody, RGD1306694 antibody, coiled-coil domain containing 88A antibody, coiled coil domain containing 88A antibody, CCDC88A antibody, Ccdc88a antibody
    背景

    Synonyms: APE, GIV, GRDN, HkRP1, GIRDIN, KIAA1212, Akt phosphorylation enhancer, Coiled-coil domain-containing protein 88A, G alpha-interacting vesicle-associated protein, Girders of actin filament, Hook-related protein 1, CCDC88A

    Background: Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. Phosphorylation of AKT1/PKB thereby induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, and regulates DNA replication and cell proliferation (By similarity). Essential for the integrity of the actin cytoskeleton and for cell migration. Required for formation of actin stress fibers and lamellipodia. May be involved in membrane sorting in the early endosome.

    基因ID
    55704
    UniProt
    Q3V6T2
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