MAP3K2 抗体 (AA 1-364)
Quick Overview for MAP3K2 抗体 (AA 1-364) (ABIN7599314)
抗原
See all MAP3K2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-364
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原理
- Anti-MEKK2/MAP3K2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MEKK2/MAP3K2 Antibody Picoband® (ABIN7599314). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MEKK2/MAP3K2 recombinant protein (Position: M1-Q364).
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) antibody
MAP3K2 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 4B4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 357-619) antibodyMAP3K2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 111-200) antibodyMAP3K2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 14-43), (N-Term) antibodyMAP3K2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34479 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (C-Term) antibodyMAP3K2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (C-Term) antibodyMAP3K2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 146-195) antibodyMAP3K2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 1-180) antibodyMAP3K2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (N-Term) antibodyMAP3K2 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 马, 豚鼠, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, Human
1. Yao Z, et al. Calcium regulation of EGF-induced ERK5 activation: role of Lad1-MEKK2 interaction. PLoS One, 2010 Sep 7. 2. Cazares LH, et al. Maging mass spectrometry of a specific fragment of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 2 discriminates cancer from uninvolved prostate tissue. Clin Cancer Res, 2009 Sep 1. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))
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别名
- MAP3K2
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背景
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Synonyms: Calcitonin, Calca, Calc
Background: MAP3K2, mitogen-activated protein kinase kinase kinase 2, also known as MEKK2, belongs to the mitogen-activated protein kinase (MAPK) kinase kinase gene family, which is involved in regulating multiple MAPK signaling pathways. Endogenous MAP3K2 localized mainly to the cytosol of unstimulated HeLa cells and rat fibroblasts. The MAP3K2 gene is mapped to chromosome 2 by the International Radiation Hybrid Mapping Consortium. MAP3K2 is a major upstream activator of the JNK, MAPK cascade. MAP3K2 was identifies as 1 of 6 kinases that regulate different steps of the caveolar cycle. Silencing of MAP3K2 strongly reduced kiss-and-run dynamics, leading to an accumulation of caveolar structures at the cell surface without affecting caveolae coat assembly or clustering.
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分子量
- 78 kDa
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基因ID
- 10746
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UniProt
- Q9Y2U5
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途径
- MAPK Pathway
抗原
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