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MAP3K2 抗体 (AA 1-364)

This 兔 多克隆 anti-MAP3K2 antibody specifically detects MAP3K2 in WB, ICC, IF 和 FACS. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN7599314
发货至: 中国
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Quick Overview for MAP3K2 抗体 (AA 1-364) (ABIN7599314)

抗原

See all MAP3K2 抗体
MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This MAP3K2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

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    AA 1-364

    原理

    Anti-MEKK2/MAP3K2 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-MEKK2/MAP3K2 Antibody (ABIN7599314). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human MEKK2/MAP3K2 recombinant protein (Position: M1-Q364).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))

    别名

    MAP3K2

    背景

    Synonyms: Calcitonin, Calca, Calc

    Background: MAP3K2, mitogen-activated protein kinase kinase kinase 2, also known as MEKK2, belongs to the mitogen-activated protein kinase (MAPK) kinase kinase gene family, which is involved in regulating multiple MAPK signaling pathways. Endogenous MAP3K2 localized mainly to the cytosol of unstimulated HeLa cells and rat fibroblasts. The MAP3K2 gene is mapped to chromosome 2 by the International Radiation Hybrid Mapping Consortium. MAP3K2 is a major upstream activator of the JNK, MAPK cascade. MAP3K2 was identifies as 1 of 6 kinases that regulate different steps of the caveolar cycle. Silencing of MAP3K2 strongly reduced kiss-and-run dynamics, leading to an accumulation of caveolar structures at the cell surface without affecting caveolae coat assembly or clustering.

    分子量

    78 kDa

    基因ID

    10746

    UniProt

    Q9Y2U5

    途径

    MAPK Pathway
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